HER2-targeted therapy shows promising results in rare bile duct cancers
Peer-Reviewed Publication
Updates every hour. Last Updated: 23-Dec-2025 15:12 ET (23-Dec-2025 20:12 GMT/UTC)
Zanidatamab, a bispecific HER2-targeted antibody, delivered clinically meaningful and durable responses for patients with HER2-positive biliary tract cancer (BTC), according to final results from the HERIZON-BTC-01 clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.
Researchers at the University of Gothenburg have discovered that milk from grey seals in the Atlantic Ocean may be more potent than breast milk. An analysis of seal milk found approximately 33 per cent more sugar molecules than in breast milk. Many of these sugars are unique and may pave the way for even better infant formula for babies.
The drug, ziftomenib. will benefit patients with recurring or treatment-resistant acute myeloid leukemia who have no other options.
Early-stage gastric cancer can be assessed more accurately using a new liquid biopsy tool that predicts lymph node metastasis, as reported by researchers from Science Tokyo. They developed a model that uses deoxyribonucleic acid (DNA) methylation biomarkers in plasma and computed tomography imaging to predict the risk of metastasis. This tool will help low-risk patients safely avoid unnecessary invasive surgery.
The SISAQOL-IMI consortium, co-led by the European Organisation for Research and Treatment of Cancer (EORTC) and Boehringer Ingelheim (BI), just announced the publication of its pivotal paper in The Lancet Oncology outlining how its recommendations for patient-reported outcomes (PROs) in cancer clinical trials were developed. Alongside the publication, the consortium has released a suite of accessible online materials designed to support researchers, clinicians, regulators, and policy makers in implementing these recommendations.