Epigenetics predicts the aggressiveness of Burkitt Lymphoma, a common pediatric tumor in developing countries
Peer-Reviewed Publication
Updates every hour. Last Updated: 5-Aug-2025 15:11 ET (5-Aug-2025 19:11 GMT/UTC)
Researchers of the Cancer Epigenetics group at the Josep Carreras Leukaemia Research Institute have discovered that patients with Burkitt lymphoma — a common paediatric tumour in equatorial African countries and Latin America — can be classified into two main groups based on their epigenetic signature. The study, a high-level international collaboration co-led by Dr Manel Esteller, has demonstrated that one group, HypoBL, has a milder course of the disease, whereas the other, HyperBL, is associated with early relapses and shorter survival.
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