Feature Articles
Oak Ridge National Laboratory
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Updates every hour. Last Updated: 1-May-2025 11:08 ET (1-May-2025 15:08 GMT/UTC)
31-Oct-2021
Journeying ‘inside’ the COVID-19 viral protein to attack a weak point
DOE/Oak Ridge National Laboratory
Researchers at the Department of Energy’s (DOE’s) Oak Ridge National Laboratory (ORNL) did to study the SARS-CoV-2 virus that caused the COVID-19 pandemic. The team used neutrons and x-rays to map part of the internal structure of the coronavirus to create an accurate 3-D model. Specifically, the scientists mapped the main protease (Mpro), an enzyme involved in the virus replication, to which they added test inhibitor molecules discovered using high-speed computer screening. One test inhibitor, labeled HL-3-68, demonstrated a superior ability to bind to and inhibit the function of Mpro compared to others that were tested. Details of the study, titled “Structural, electronic and electrostatic determinants for inhibitor binding to subsites S1 and S2 in SARS-CoV-2 main protease,” are published in the Journal of Medicinal Chemistry.
- Journal
- Journal of Medicinal Chemistry
15-Oct-2021
Quick detection of uranium isotopes helps safeguard nuclear materials
DOE/Oak Ridge National Laboratory
Analytical chemists at the Department of Energy’s Oak Ridge National Laboratory have developed a rapid way to measure isotopic ratios of uranium and plutonium collected on environmental swipes, which could help International Atomic Energy Agency analysts detect the presence of undeclared nuclear activities or material.
- Journal
- Analytical Chemistry
- Funder
- US Department of Energy National Nuclear Security Administration
6-Oct-2021
Brown takes new role with Climate Change Science Institute at ORNL
DOE/Oak Ridge National Laboratory
Marilyn Brown of the Georgia Institute of Technology recently began a joint faculty appointment, or JFA, with the Climate Change Science Institute at the Department of Energy’s Oak Ridge National Laboratory. As an internationally recognized leader in climate solutions and energy policy, Brown will collaborate with ORNL to apply insights from global climate science to inform regional strategies that reduce carbon emissions and equitably address impacts on communities.
1-Oct-2021
Energy Secretary Granholm visits ORNL in virtual tour of world-class science facilities
DOE/Oak Ridge National Laboratory
On Sept. 28, U.S. Secretary of Energy Jennifer Granholm joined leadership and top scientists and engineers online at Oak Ridge National Laboratory for a two-hour whirlwind tour. At 14 stops, researchers highlighted the lab’s world-class facilities and projects that enable leading-edge scientific discoveries and innovations that address some of the nation’s most compelling scientific and technical challenges.
1-Oct-2021
Perfecting the pellet
DOE/Oak Ridge National Laboratory
A team of experts at Oak Ridge National Laboratory is taking aim at one of the biggest challenges facing the international ITER fusion facility: turning cold gas into wine-cork-sized, solid pellets to help keep ITER’s plasma in check.
30-Sep-2021
Microbial “theft” enables breakdown of methane, toxic methylmercury
DOE/Oak Ridge National Laboratory
A team led by the Department of Energy’s Oak Ridge National Laboratory and the University of Michigan has discovered that certain bacteria can steal an essential compound from other microbes to break down methane and toxic methylmercury in the environment.
- Funder
- DOE/US Department of Energy
23-Sep-2021
Laser treatment shows potential for reducing industrial chemical processing for vehicles
DOE/Oak Ridge National Laboratory
A multidisciplinary team of scientists at the Department of Energy’s Oak Ridge National Laboratory has applied a laser-interference structuring, or LIS, technique that makes significant strides toward eliminating the need for hazardous chemicals in corrosion protection treatments. The novel application of the LIS method answers a call from the U.S. Department of Defense for research projects that explore nonchemical alternatives for corrosion protection in military vehicles and aircraft systems.
- Journal
- CORROSION
- Funder
- U.S. Department of Defense
17-Sep-2021
ORNL expertise supports latest IPCC report and efforts to understand, address climate change
DOE/Oak Ridge National Laboratory
Improved data, models and analyses from Oak Ridge National Laboratory scientists and many other researchers in the latest global climate assessment report provide new levels of certainty about what the future holds for the planet and highlight the urgency of decarbonization to avoid the most severe impacts.
- Funder
- DOE/US Department of Energy, DOE/US Department of Energy
17-Sep-2021
Living laboratory, biodiversity hub: The Oak Ridge National Environmental Research Park
DOE/Oak Ridge National Laboratory
Nestled at the intersection of eastern Tennessee’s Anderson and Roane Counties, the Oak Ridge National Environmental Research Park is a living laboratory and a major resource for conducting ecological studies.
- Funder
- DOE/US Department of Energy