In Nature, a team led by researchers at the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National Laboratory (Berkeley Lab) uncovered a broad diversity of large and giant viruses that belong to the nucleocytoplasmic large DNA viruses (NCLDV) supergroup. As a result, virus diversity in this group expanded 10-fold from just 205 genomes, redefining the phylogenetic tree of giant viruses.