KAIST Develops Core Technology to Reverse Biological Changes Once Thought Irreversible, Opening New Possibilities for Aging and Cancer Research (IMAGE)
Caption
[Figure 2] Process of identifying the irreversibility kernel and deriving control strategies using ROOT
Using a logic-based molecular regulatory network of an irreversible biological phenomenon as input, Professor Kwang-Hyun Cho's research team extracted the irreversible state-transition pathway, identified the irreversibility kernel — the core circuit that sustains irreversibility — and, based on this, derived optimal control strategies that either restore cells to their previous state or eliminate irreversibility.
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