Researchers have uncovered a hormone-sensitive neural circuit between the hypothalamic medial preoptic area and paraventricular nucleus that, when modulated, powerfully alters depressive-like behaviors in a mouse model of postpartum depression, pointing to a promising target for future treatments.

This study shows that oral—but not intravenous—lysozyme reshapes gut microbiota to reactivate PI3K–Akt signaling and reverse vascular aging in mice, revealing a gut–vascular inflammatory aging axis and pointing to potential noninvasive therapies for age-related vascular disease.

Recently, a research team from Chongqing Medical University, led by Prof. Wei Huang, Dr. Wei Bao, and Dr. Yiting Lei, has successfully developed a novel engineered extracellular matrix (eECM) to address the challenge of cartilage repair. Their findings were published in Research under the title "Cytokine-Activated MSC-Derived ECM Facilitates Cartilage Repair by Maintaining Chondrocyte Homeostasis and Promoting Chondrogenic Differentiation of Recruited Stem Cells."

Recently, to address this issue, the research group led by Qian Xiang from the Division of Intelligent Instruments and Equipment at Tsinghua Shenzhen International Graduate School proposed a flexible electret tactile feedback actuator based on multi-layer variable stiffness polydimethylsiloxane (PDMS) elastomers.