Researchers discovered that an A216V mutation in the unrearranged PML allele confers resistance to arsenic trioxide in acute promyelocytic leukemia, revealing a hidden cause of relapse and underscoring the need for genetic screening to guide personalized treatment.

Scientists have conducted a study of the predatory behavior of sharks in deep-sea ecosystems. This research provides insights into the behavior and distribution range of Pacific sleeper sharks. The research is published in the journal Ocean-Land-Atmosphere Research on June 1, 2025.

A comprehensive review reveals that blocking natural killer cell checkpoints and employing precision strategies like gene editing and engineered cell therapies could significantly enhance cancer immunotherapy outcomes for solid tumors and blood cancers.

The research team proposed a novel discrete-modulated coherent-state quantum key distribution with basis encoding. In this scheme, Alice performs discrete modulation on the coherent state and sends it to Bob. Bob performs coherent detection and encodes the key in the base selection, ultimately publishing the measurement results.