Elevated dickkopf 3 promotes abdominal aortic aneurysm formation via modulated phenotype switch of vascular smooth muscle cells
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Updates every hour. Last Updated: 6-Nov-2025 17:11 ET (6-Nov-2025 22:11 GMT/UTC)
Recently, Wei Tao Huang Research Team published a groundbreaking study in the journal Research, introducing a multifunctional trimetallic gold–silver–chromium nanocomposite (Au–Ag–Cr NCs). These nanocomposites have been applied in various fields, including multimode and multianalyte sensing, advanced arithmetic and reversible logic operations, and large-scale information security protection. This study not only updates the preparation paradigm of multimetallic nanomaterials but also paves the way for new applications in molecular information technology.
Led by Professor Junya Wang at Huazhong University of Science and Technology, the team has pushed the envelope by introducing a method inspired by human visual “gaze” behavior. Instead of hardware upgrades, their solution dynamically adjusts the MEMS scanning trajectory so that, within a fixed sampling budget, more attention is directed toward regions of interest (ROIs).
July 10, 2025 - A research team led by Professor Yiwei Li and Professor Bi-Feng Liu from the College of Life Science and Technology at Huazhong University of Science and Technology (HUST) published an important research article titled "Mechanical Cell Reprogramming on Tissue-Mimicking Hydrogel for Cancer Cell Transdifferentiation" in the journal Research. The paper can be accessed through this link: https://spj.science.org/doi/10.34133/research.0810.
Professor Yiwei Li and Professor Bi-Feng Liu serve as corresponding authors, with doctoral students Xueqing Ren and Research Scientist Dr. Yachao Wang as co-first authors.
This study developed an innovative tissue-mimicking hydrogel system that achieves cell reprogramming through purely mechanical signals for the first time. The technology not only enhances the stemness and bidirectional differentiation potential of fibroblasts but also promotes cancer cell transdifferentiation into adipocytes, providing novel therapeutic strategies for regenerative medicine and cancer treatment.