A revolution in cancer rehabilitation powered by robotic exoskeletons
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Dec-2025 14:11 ET (22-Dec-2025 19:11 GMT/UTC)
A growing body of evidence indicates that the microbiome within the gut and tumors significantly influences cancer initiation, progression, and treatment response. Current research primarily focuses on bacteria, whilst the role of fungi is only now gaining attention. The authors address key questions that have caused confusion and hindered clinical translation: (a) Why should we value the role of mycobiome in oncological research? (b) What will the relationship between fungi and bacteria be in cancer progression? (c) How will the fungi impact cancer? (d) Can we target fungi for development of intervention strategies in anticancer treatment? (e) Will the effort and investment pay back in mycobiome-driven cancer research?
Recently, research teams led by Professor Cai Songhua from the Shenzhen Branch of the Cancer Hospital of the Chinese Academy of Medical Sciences, Professor Mao Wenjun from Wuxi People's Hospital, and Professor Tang Bufu from Zhongshan Hospital affiliated to Fudan University have focused on the immune microenvironment and lung cancer radiotherapy. They demonstrated a combined therapeutic approach targeting SPP1+ macrophages to enhance radiotherapy sensitivity, with the findings published under the title“ SPP1+ TAM: CD8+ T cell crosstalk associates with blocking radiotherapy efficacy in lung cancer” on Research.
Recently, Professor Jie Kong, Associate Professor Jin Liang, and their research team from Northwestern Polytechnical University have systematically reviewed the design strategies, printing processes, and application progress of magnetically responsive materials in 4D printing. This study thoroughly analyzes the working principles and performance optimization methods of magnetically responsive shape memory materials, and demonstrates their innovative applications in fields such as biomedical tissue engineering, robotics, and intelligent devices. The relevant work was published in Research under the title "4D Printing of Magnetically Responsive Materials and Their Applications" (Research, 2025, DOI: 10.34133/research.0847).