Novel insights into Candida glabrata in pregnant women's reproductive tracts in Hainan: prevalence, drug resistance, and genetic diversity
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Updates every hour. Last Updated: 1-May-2025 05:08 ET (1-May-2025 09:08 GMT/UTC)
In a study set to be published in Mycology, a research team led by Prof. Jianping Xu from McMaster University and researcher Jinyan Wu from Hainan Medical University presents new findings on Candida glabrata in pregnant women in Hainan. This research focuses on understanding the prevalence, drug resistance, and genetic characteristics of this fungus, which has significant implications for maternal and fetal health.
Efforts to improve the performance of protonic ceramic fuel cells (PCFCs) have been hampered by the limited availability of cathode materials with high activity and durability. One potential approach to enhance electrocatalytic performance is by modifying the particle morphology of the cathode, which potentially reforms transport properties and active reaction sites. The team of material scientists led by Jie Hou from University of South China attempted to configure cathode particles through the controlled growth of cubes, aiming to improve the properties of perovskite-related Pr1.5Ba1.5Cu3O7 (PBC). This study demonstrates the potential of controlling particle growth to design highly-active electrodes with specialized properties, opening new avenues for material design in PCFCs and related electrocatalytic fields.
In a paper published in Mycology, researchers investigated the adaptive mechanisms of Microsporum canis, a dermatophyte transitioning from animal to human hosts. Using comparative genomics, the study identified key genetic features, including expanded gene families and altered protease activity, that enhance adaptation to human skin. This work sheds light on the evolutionary dynamics of dermatophytes and their interactions with diverse hosts, offering insights for managing fungal infections.
The core of this article is to explore the mechanism by which the ruthenium (Ru) integration effect influences ruthenium-cobalt (RuCo) bimetallic nanoparticles in enhancing water-splitting properties. The research team synthesized RuCo bimetallic nanoparticles (RuCo@NC) with atomically dispersed Ru on nitrogen-doped carbon. They found that atomically dispersed Ru not only serves as the primary active site for the hydrogen evolution reaction (HER) but also promotes the oxidation of the Co surface to CoOOH*, thereby becoming a highly active site for the oxygen evolution reaction (OER). The optimized catalyst, RuCo@NC-1, exhibited outstanding performance. In alkaline conditions, it required only 217 and 96 mV of overpotential to reach a current density of 10 mA‧cm−² for OER and HER, respectively. This study offers valuable insights into the design of Ru-based electrocatalysts for water splitting.
In this study, the controllable synthesis of highly stable Ag56 clusters was achieved using 4-vinylbenzoic acid (abbreviated as p-VBA) and tert-butyl mercaptan as ligands by precisely regulating reaction parameters such as temperature and solvent. Furthermore, the intermediates Ag20, Ag31, Ag32 and the dimers of the intermediate Ag31/Ag32, Ag30-bpbenz (bpbenz, 1,4-di(4-pyridyl)benzene) and Ag31-bpe (bpe, 1,2-bis(4-pyridyl)) were successfully captured. This series of nanoclusters exhibited a unique fluorescence aggregation-induced redshift phenomenon as the π–π interaction of the ligand. In addition, the Ag₅₆ nanocluster can be used as near infrared fluorescence sensors for Br−/I− and their detection limits were as low as 85 and 105 nM, respectively. The results of this study provide new ideas and methods for the synthesis of metal clusters and their applications in the field of ion sensing.
Monoclonal antibodies like etesevimab have lost efficacy against Omicron subvariants, necessitating innovative solutions. George Fu Gao's team developed BAADesign, a strategy combining structural analysis, computational design, and experimental validation to restore antibody activity. Using this method, they reengineered etesevimab into CB6-IV, achieving broad-spectrum neutralization against Omicron subvariants.
High-entropy carbides (HECs) exhibit exceptional mechanical properties and ultrahigh thermal stability, making them promising materials for high-temperature extreme environments, such as hypersonic vehicles and nuclear reactors. The fabrication of complex-shaped components for these applications involves the HECs joints and requires these joints capable of withstanding extreme service temperatures. However, developing such joints presents significant challenges: the stability and sluggish diffusion characteristics of HECs hinder solid-phase diffusion, while using liquid alloys at bonding interfaces typically introduces low-melting-point compounds that compromise thermal durability. Consequently, developing HEC joints with superior high-temperature endurance remains a critical challenge in materials engineering.
Timely monitoring abnormal gaits of teenagers is crucial for their physical health and development. Triboelectric nanogenerators (TENGs) are widely used in the wearable field. Choosing high-performance and safe triboelectric materials to monitor abnormal gaits remains challenging. Polyoxometalates (POMs) nanomaterials can effectively serve as triboelectric materials due to rich surface morphology and large specific surface area. The team designed a TENG using POMs nanorods as triboelectric materials by changing the morphology of POMs, achieving an improvement in TENG performance. The optimized TENG has achieved significant results in gait monitoring of teenagers, promoting research in this field.
MXene, as a rising star among two-dimensional electromagnetic wave materials, faces urgent challenges in addressing its self-stacking issue and regulating its conductivity. Herein, a micro-macro collaborative design strategy was proposed to regulate heterogeneous interface engineering in MXene-based absorbers. Biomass-based cotton was introduced as three-dimensional (3D) framework for constructing a porous structure, TiO2 was in-situ generated and nitrogen atom was doped on Ti3C2Tx MXene to regulate its dielectric properties, a 3D N-doped carbon fiber/MXene/TiO2 (N-CMT) nano-aerogel was successful constructed. The synergistic effects of diverse components and structural designs, porous frameworks and TiO2 lattice contraction can significantly adjust the density of the conductive network and create abundant heterogeneous interfaces, as well as the lattice defects induced by nitrogen atom doping can enhance polarization loss, ultimately leading to the excellent microwave absorption performance of 3D N-CMT nano-aerogels. The optimized N-CMT 30% aerogel exhibited a minimum reflection loss of −72.56 dB and an effective absorption bandwidth of 6.92 GHz at 2.23 mm. These results demonstrate that 3D N-CMT nano-aerogel relying on interface engineering design exhibits significant potential in the field of electromagnetic protection, providing an important reference for future efficient absorbers.