Formaldehyde releasers found in common personal care products
Peer-Reviewed Publication
Updates every hour. Last Updated: 14-Aug-2025 07:11 ET (14-Aug-2025 11:11 GMT/UTC)
Growing concerns about exposure to formaldehyde in personal care products have focused on hair relaxers with recent studies showing a link between use of hair relaxers and increased risk of uterine and breast cancer among Black women. The new study is among the first to demonstrate that formaldehyde-releasing preservatives are present in a wide range of personal care products, including shampoo, lotions, body soap, and even eyelash glue.
Bladder cancer (BCa), one of the most common and deadly malignancies of the urinary system, is characterized by high rates of recurrence and rapid progression. Exosomes and long non-coding RNAs (lncRNAs) are key players in tumor development, with lncRNAs comprising 3.36% of the total RNA content in exosomes. Although exosomal lncRNAs are essential regulators of BCa, their underlying mechanisms remain poorly understood.
Acute myeloid leukemia (AML) is an aggressive blood cancer characterized by the uncontrolled proliferation of malignant hematopoietic stem and progenitor cells. METTL3, a key catalytic component within the m6A methyltransferase complex (alongside METTL14), is overexpressed in AML cells and plays a crucial role in promoting cancer. However, effective pharmacological targeting of the RNA m6A transferase core complex remains a challenge.
Background: Percutaneous lung biopsy (PLB) is currently widely utilized in the diagnosis and treatment of lung tumors, owing to its advantages of minimal trauma, high detection rate, and precise localization. However, traditional computed tomography (CT)-guided freehand PLB procedures often involve multiple puncture adjustments and a relatively high incidence of complications. The aim of this study is to investigate whether laser-guided technology can effectively reduce the operative time and incidence of complications.
Methods: This study included 141 patients who underwent CT-guided PLB at the First Affiliated Hospital of Soochow University between January 2022 and January 2024. These patients were divided into two groups based on the use of laser-guided technology during the procedure: the laser-guided group (47 patients) and the manual group (94 patients). Clinical data from all patients were collected. Information such as the success rate of biopsy procedures and the incidence of complications was analyzed and compared.
Results: The procedure time in the laser-guided group was shorter than that in the manual group (P=0.008). In the laser-guided group, the number of adjustments needed to reach the tumor during the positioning step was less than the manual group (P=0.001). In the laser-guided group, the number of CT scans performed before reaching the tumor was smaller than in the manual group (P=0.01). The distance from the first puncture to the lung tumor in the laser-guided group was closer than that in the manual group (P=0.049). The laser-guided group had a smaller angular deviation from the target at the first puncture than the manual group (P=0.004).
Conclusions: Laser-guided technology has the advantages of shorter operation time and less adjustment of biopsy needles. However, laser-guided technology does not reduce the complication rate of biopsy surgery or the length of hospital stay after surgery and there is no statistical difference in the accuracy of pathological diagnoses obtained by the two methods.
Keywords: Laser-guided technology; percutaneous lung biopsy (PLB); lung cancer; pulmonary nodules