EurekAlert! Cancer Research

News Releases

Updates every hour. Last Updated: 4-Nov-2026 05:16 ET (4-Nov-2026 10:16 GMT/UTC)

29-Jun-2026

New laboratory tool opens door to better treatments for rare and deadly melanomas

University of Turku
Peer-Reviewed Publication

Researchers have created a powerful new cellular model to study rare tumours that are resistant to immunotherapies. The tool could change how therapies are developed for aggressive melanomas that currently have almost no effective treatment options.

Journal: Communications Biology

28-Jun-2026

Abnormally long mitochondria leak RNA: activating anti-tumor immunity

The University of Osaka
Peer-Reviewed Publication

Researchers from the University of Osaka have demonstrated that mitochondrial hyperfusion, when induced by low levels of DRP1 or cellular stress, activates an immune response through the RIG-I–MAVS pathway. Dependent on the involvement of the BAX protein, the release of mitochondrial RNA into the cytosol enhanced natural killer cell cytotoxicity and reduced tumor growth in a xenograft model. The findings provide new possibilities for cancer research and treatment.

Journal: Cell Reports
Funder: Japan Society for the Promotion of Science, Japan Agency for Medical Research and Development

28-Jun-2026

KAIST identifies new therapeutic target by revealing how cancer ‘hijacks’ the blueprint for blood vessel development

The Korea Advanced Institute of Science and Technology (KAIST)
Peer-Reviewed Publication

hijacks the gene regulatory blueprint of normal vascular differentiation to drive tumor angiogenesis —without evolving an entirely new mechanism.

single-cell multi-omics and a 3D gene regulatory map built from an hESC-based vascular differentiation system, the team pinpointed the late progenitor stage as the developmental origin of tumor endothelial cell identity.

receptor (ITGAV) was identified as a key mediator and validated as a therapeutic target: its inhibition suppressed tumor vascularization and growth in a colorectal cancer model.

Funder: National Research Foundation of Korea, Institute for Basic Science

28-Jun-2026

Low grip strength should not be used as an independent predictor of prostate cancer in older men

University of Sharjah
Peer-Reviewed Publication

New research suggests that although low hand grip strength is a valuable indicator of overall health and frailty, it is not a reliable standalone predictor of increased prostate cancer risk among older men.

Journal: Maturitas

28-Jun-2026

Myelodysplastic syndrome with CD34+ micromegakaryocytes and giant platelets in peripheral blood

Xia & He Publishing Inc.
Peer-Reviewed Publication

Myelodysplastic syndromes (MDS) are a group of hematopoietic disorders characterized by ineffective hematopoiesis, with manifestations of cytopenias in one, two, or three lineages. CD34⁺ micromegakaryocytes and giant platelets are very rarely seen in MDS patients but may lead to unnecessary treatments. Therefore, we report and follow up on an MDS case with such an unusual finding.

Journal: Journal of Clinical and Translational Pathology

27-Jun-2026

Heterogeneous phenotype of acute leukemia with EWSR1 or FUS gene rearrangements

Xia & He Publishing Inc.
Peer-Reviewed Publication

Acute leukemias with chimeric fusion genes involving FET (FUS, EWSR1, and TAF15) family proteins and ETS (E26 transformation-specific)-like transcription factors often present with unique clinical and pathological characteristics. This mini-review aims to summarize the clinical and pathological features of acute leukemia cases harboring rearrangements involving the fused in sarcoma (FUS) or Ewing sarcoma breakpoint region 1 (EWSR1) genes.

Journal: Journal of Clinical and Translational Pathology

26-Jun-2026

VCU Massey Comprehensive Cancer Center researchers lead multi-decade analysis of new cancer incidence among survivors

Virginia Commonwealth University
Peer-Reviewed Publication

As people continue to live longer and the survival rate of cancer diagnoses increases, researchers from VCU Massey Comprehensive Cancer Center led a multi-decade analysis studying the rates of subsequent primary cancers (SPCs), which are new cancers unrelated to the original diagnosis. The study, which was recently published in PLOS Medicine, provides understanding for how these cancer risks change over time and across generations, helping guide future prevention and monitoring measures.

A team of Massey researchers used cancer registry data from over three million cancer survivors in the United States from 1975-2021 to study patterns of SPCs, examining age, calendar period and birth cohort effects on SPC risk.

Journal: PLOS Medicine

26-Jun-2026

Rare but real: Why a common skin cancer can hide on a finger

Higher Education Press
Peer-Reviewed Publication

A rare case of basal cell carcinoma (BCC) on the right middle finger in a 63-year-old man underscores that this common skin cancer can occur in unusual digital locations. The report emphasizes that biopsy remains the gold standard for diagnosis, and clinicians should include BCC in the differential diagnosis of atypical finger lesions to ensure timely treatment.

26-Jun-2026

Artificial intelligence in breast pathology: Recent advances in multimodal models, explainability, and clinical applications

Xia & He Publishing Inc.
Peer-Reviewed Publication

Artificial intelligence (AI) is increasingly reshaping diagnostic pathology, with breast pathology representing one of the most advanced and clinically impactful areas of adoption. Despite rapid progress, many practicing pathologists remain unfamiliar with core AI concepts and their practical implications. This review provides a concise and accessible overview of AI in breast pathology, focusing on foundational principles, current clinical applications, and future directions.

Journal: Journal of Clinical and Translational Pathology

26-Jun-2026

Breast milk, best sleep: Nationwide Japanese study finds

Toyama Regional Center for the Japan Environment and Children's Study, University of Toyama
Peer-Reviewed Publication

In contrast to the misconception that breastfed babies sleep less as breastmilk is easily digested, a new study of 82,918 infants found that children who received breast milk during the first six months of life were less likely to experience short sleep duration at one year of age than those who were exclusively fed formula. Using data from the Japan Environment and Children’s Study, the researchers proposed biological mechanisms that may help explain this association.

Journal: European Journal of Clinical Nutrition
Funder: Ministry of the Environment