Researchers at Weill Cornell Medicine, Cedars-Sinai Medical Center, and Roswell Park Comprehensive Cancer Center have developed genetically engineered CAR T cells that specifically target and kill bladder cancer cells. The study, to be published June 26 in the Journal of Experimental Medicine (JEM), demonstrates that direct delivery of these CAR T cells via a catheter can control bladder tumors in mice, raising hopes that a similar approach may be effective in humans.

Nanomedicines often acquire a protein corona in the bloodstream before reaching the brain. A new Perspective in Science Bulletin argues that this evolving layer should be engineered as a programmable interface that can guide recognition, transcytosis and release across the blood-brain barrier.

Histopathology is a cornerstone of clinical diagnosis, especially in cancer care. However, conventional chemical staining is often time-consuming and labor-intensive and may consume precious tissue samples. A cross-disciplinary research team at The Hong Kong University of Science and Technology (HKUST) has developed a novel generative AI (GenAI) framework that can produce high-fidelity virtually stained images even when training image pairs are imperfectly aligned, paving the way for faster and more tissue-saving histopathology workflows. The study titled “Generative AI for misalignment-resistant virtual staining to accelerate histopathology workflows” was recently published in the international journal Nature Communications. 

Researchers invent a laser technique that reveals the hidden forces shaping proteins, advancing a future of precision medicine engineered with quantum precision.

A chemotherapy drug and a gene-silencing molecule exploit an “eat me” signal on dying cancer cells to stop tumor growth.