High-fat diet promote breast cancer metastasis in animal models
Peer-Reviewed Publication
Updates every hour. Last Updated: 14-Aug-2025 14:11 ET (14-Aug-2025 18:11 GMT/UTC)
CNIO researchers discover that, in mice that eat a lot of fat, cancer cells travelling through the blood surround themselves with platelets, which act as an armor-like protection as they spread.
In addition, in animals with a fatty diet it is easier for tumor cells to 'nest' in other organs and give rise to metastasis of the primary tumor.
“These results anticipate a future in which dietary changes, together with the control of platelet activity, will complement antitumor treatments,” says Héctor Peinado, of the Spanish National Cancer Research Center (CNIO).
The study is published in 'Nature Communications’.
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