EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 1-May-2025 05:08 ET (1-May-2025 09:08 GMT/UTC)

Pregnancy-related proteins in tumors linked to worse survival in female lung cancer patients

Memorial Sloan Kettering Cancer Center
Reports and Proceedings

Lung cancer co-opts genes that normally help a fetus develop and evade the mother’s immune system — leading to poorer outcomes in female patients, an MSK research team has found.

Meeting: AACR Annual Meeting 2025

Making magnetic biomaterials

University of Pittsburgh
Peer-Reviewed Publication

Researchers at the University of Pittsburgh have developed silk iron microparticles (SIMPs)—magnetic, biodegradable carriers designed to deliver therapies directly to disease sites like aneurysms or tumors. The particles are created by chemically bonding iron oxide nanoparticles to regenerated silk fibroin using glutathione, enhancing their magnetic responsiveness while maintaining biocompatibility. These nanoscale carriers, roughly one-hundred-thousandth the width of a human hair, can potentially be guided externally to precise locations in the body. The platform enables localized delivery of therapeutic agents such as extracellular vesicles, regenerative factors, or drugs, offering a minimally invasive approach to treating conditions like abdominal aortic aneurysms and expanding the potential for targeted therapies in regenerative medicine.

Journal: ACS Applied Materials & Interfaces

Disparities in breast reconstruction persist after ACA, reports Plastic and Reconstructive Surgery

Wolters Kluwer Health
Peer-Reviewed Publication

Despite steady increases in rates of immediate breast reconstruction (IBR) after mastectomy, racial disparities in IBR have persisted in the years since implementation of the Affordable Care Act (ACA), reports a study in the May issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.

Journal: Plastic & Reconstructive Surgery

CAD/CAM shows clinical benefits in jaw reconstruction, reports Plastic and Reconstructive Surgery

Wolters Kluwer Health
Peer-Reviewed Publication

For patients undergoing jaw reconstruction after surgery for head and neck cancer, computer-aided design and manufacturing (CAD/CAM) techniques can improve some key clinical outcomes, reports a study in the May issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.

Journal: Plastic & Reconstructive Surgery

New study highlights success of financial toxicity tumor board in reducing cancer treatment costs

Atrium Health Wake Forest Baptist
Peer-Reviewed Publication

Financial toxicity, the financial distress linked to cancer treatment, significantly impacts patient outcomes. To combat this, the Atrium Health Levine Cancer Institute established a Financial Toxicity Tumor Board in 2019.

The board is the first known institutional-level intervention of its kind, functioning like a traditional disease-focused multidisciplinary tumor board, but with a singular focus on financial distress. It includes participants from all areas of the cancer center including clinical, supportive and administrative domains.

Journal: Journal of the National Comprehensive Cancer Network

AACR: New CAR T cell therapy benefits patients with advanced thyroid cancers

University of Texas M. D. Anderson Cancer Center
Reports and Proceedings

Phase I trial demonstrates lasting responses and encouraging safety profile in two aggressive thyroid cancer subtypes, suggesting further progress for CAR T cell therapy in solid tumorsOne patient experienced a complete response, and one patient had a partial response. This type of cancer has limited treatment options, and most patients have a poor prognosis of six months or less. AIC100 is a CAR T cell therapy that targets the ICAM-1 protein on tumor cells.

Meeting: AACR Annual Meeting 2025

Researchers reveal how human genetics and intratumoral microbiota affect colorectal cancer

Chinese Academy of Sciences Headquarters
Peer-Reviewed Publication

A recent study led by the Guangzhou Institutes of Biomedicine and Health of the Chinese Academy of Sciences has focused on this relationship and its effect on colorectal cancer. The study shows that the single-nucleotide polymorphism rs2355016—a tiny DNA change that some people carry—affects how intratumoral microbiota adhere to tumor cells, promoting CRC progression.

Journal: Cell Host & Microbe

Surviving cancer, still suffering: Survey reveals gaps in follow‑up care

Northwestern University
Peer-Reviewed Publication

More Americans are beating cancer than ever, yet many still grapple with treatment’s long shadow — especially on their mental health.

A new Northwestern Medicine study found most head-and-neck cancer survivors who underwent radiation don’t know about “survivorship care,” even as many grapple with side effects such as lingering dry mouth, swallowing problems and psychological distress.

Journal: Supportive Care in Cancer
Funder: NIH/National Center for Advancing Translational Sciences (NCATS)

HonorHealth Research Institute is the first of 50 sites worldwide to treat a patient in a new clinical study aimed at melanoma

HonorHealth Research Institute
Peer-Reviewed Publication

This Phase III trial is based on a Phase I trial of patients in which the engineered cells were shown to be safe and effective, with minimal side effects. Initial study results were published April 9 in the scientific journal Nature Medicine.

Journal: Nature Medicine

HonorHealth Research Institute presents new findings in decades-long quest to conquer aggressive pancreatic cancer

HonorHealth Research Institute
Reports and Proceedings

Study findings indicate that a newly discovered drug, RMC-6236, also known as Daraxonrasib, is a powerful inhibitor of RAS (including KRAS, NRAS and HRAS). This study evaluated the effectiveness of RMC-6236 in patient-derived pancreatic tumors harboring KRAS mutations.

Meeting: AACR Annual Meeting 2025

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