Repackaged cancer drug boosts delivery to tumors, improves combination therapies
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Sep-2025 11:11 ET (22-Sep-2025 15:11 GMT/UTC)
University of Arizona researchers devised a new method to deliver cancer chemotherapy drugs to pancreatic and breast cancer tumors more effectively and with less damage to healthy tissues than standard forms of chemotherapy. They repackaged the drug paclitaxel, creating a new formulation that may help overcome some common limitations of chemotherapy drugs, including toxicity, setting the stage for a promising new platform for treating cancer and other diseases.
A new study published in the journal Nature Genetics maps out the timeline of DNA damage for multiple myeloma. The findings may lead to better ways to group patients by the state of their DNA and define new subtypes of disease to better predict treatment strategies and outcomes.
OKLAHOMA CITY – Large cell neuroendocrine carcinoma (LCNEC), a rare and aggressive type of lung cancer, has a high chance of metastasis, no standard treatment and a poor survival rate. A study published in Nature Communications provides a new understanding of the disease and uncovers a potential target for treatment.
Study finds cancer cells break down protective nerve coverings, leading to nerve injury and chronic inflammation
These nerve injuries drive immune exhaustion and immunotherapy resistance
Targeting the cancer-induced nerve injury pathway can reverse resistance and improve treatment response
Findings highlight importance of studying cancer neuroscience – the interactions between cancer and the nervous system
Blocking brain damage triggered by a glioblastoma, an aggressive brain cancer, may slow the growth of the cancer and allow the brain to keep working better for longer, according to a new study led by UCL (University College London) researchers.
When triple-negative breast cancer grows, the fat cells around it seem to shrink.
UCSF researchers have discovered that the cells of these tumors, which are among the deadliest types of breast cancer, build molecular tunnels, called gap junctions, into nearby fat cells. The tumor cells then send instructions that trigger the fat cells to release stores of energy that could feed the cancer.