EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 6-May-2025 15:09 ET (6-May-2025 19:09 GMT/UTC)

Oxytocin system of breastfeeding affected in mothers with postnatal depression

University College London
Peer-Reviewed Publication

The oxytocin system – which helps release breast milk and strengthens the bond between mother and baby – may be affected during breastfeeding in mothers experiencing postnatal depression, finds a new study by UCL researchers.

Journal: Psychoneuroendocrinology

Pitt study makes new insights into the origins of ovarian cancer

University of Pittsburgh
Peer-Reviewed Publication

Researchers at the University of Pittsburgh have identified a novel trigger of a deadly form of ovarian cancer: a subset of progenitor cells that reside in fallopian tube supportive tissue, or stroma.

Journal: Cancer Discovery
Funder: NIH/National Institutes of Health, U.S. Department of Defense, Honorable Tina Brozman Foundation

ESMO Sarcoma and Rare Cancers Congress 2025: Event announcement

European Society for Medical Oncology
Meeting Announcement

The ESMO Sarcoma and Rare Cancers Congress 2025, to be held from 20-22 March in Lugano, Switzerland, will be the convergence point for world-renowned experts to present and discuss developments in the diagnosis and treatment of rare solid tumours.

Promising new therapeutic approach for pediatric brain tumors

Medical University of Vienna
Peer-Reviewed Publication

Brain tumours remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than 18 months after diagnosis and limited treatment options. A research team from MedUni Vienna/University Hospital Vienna, the Dana-Farber Cancer Institute and the University of Michigan Medical School identified Platelet-Derived Growth Factor Receptor Alpha (PDGFRA) as a promising therapeutic approach. The study has just been published in the scientific journal "Cancer Cell".

Journal: Cancer Cell

Small messengers called extracellular vesicles deliver molecules between cells using protein signal

Institute for Glyco-core Research (iGCORE), Tokai National Higher Education and Research System
Peer-Reviewed Publication

Most cells in the body send out little messengers called extracellular vesicles that carry proteins, lipids, and other bioactive molecules to other cells, playing an important role in intercellular communication. But healthy cells are not the only ones that rely on extracellular vesicles. Cancer cells do, too. Small extracellular vesicles that are shed from tumor cells contribute to how cancer spreads to healthy tissue.

Journal: Nature Communications

Chinese researchers develop system for predicting hepatocellular carcinoma recurrence

Chinese Academy of Sciences Headquarters
Peer-Reviewed Publication

A research team led by Prof. SUN Cheng from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, along with collaborators from the Agency for Science, Technology, and Research and the Chinese Academy of Agricultural Sciences, has developed a novel spatial immune-based prediction system for assessing the risk of hepatocellular carcinoma (HCC) recurrence.

Journal: Nature

Cellular circuit controls how DNA damage is repaired, affecting risk of disease as we age

Sanford Burnham Prebys
Peer-Reviewed Publication

Scientists at Sanford Burnham Prebys and collaborators across the country published findings March 5, 2025, in Nature Communications showing that the mitochondria powering our cells also control the ability of a DNA repair protein to suppress the senescence-associated secretory phenotype (SASP), which causes zombie-like cells to spew inflammatory molecules that can contribute to chronic inflammation in the body.

Journal: Nature Communications
Funder: NIH/National Institutes of Health, NIH/National Cancer Institute, California Institute for Regenerative Medicine

Re-purposed FDA-approved drug could help treat high-grade glioma

Michigan Medicine - University of Michigan
Peer-Reviewed Publication

A study, published in Cancer Cell, shows that high-grade glioma tumor cells harboring DNA alterations in the gene PDGFRA responded to the drug avapritinib, which is already approved by the United States Food and Drug Administration to treat gastrointestinal stromal tumors with a PDGFRA exon 18 mutation as well advanced systemic mastocytosis and indolent systemic mastocytosis.

Journal: Cancer Cell
Funder: NIH/National Institutes of Health, NIH/National Cancer Institute, Austrian Science Fund

Eat better, breathe easier? Research points to link between diet, lung cancer

University of Florida
Peer-Reviewed Publication

A new study shows how the lungs respond to poor diet.

Journal: Nature Metabolism

Faeth Therapeutics and The Gog Foundation, Inc. (GOG-F) launch first phase 2 combination trial for sapanisertib-serabelisib in patients with endometrial cancer

The GOG Foundation Inc
Business Announcement

Faeth Therapeutics (Faeth), a clinical-stage biotechnology company focused on metabolism, and The GOG Foundation, Inc. (GOG-F), a not-for-profit organization with the purpose of promoting excellence in the quality and integrity of clinical and translational scientific research in the field of gynecologic malignancies, today announced the first patient has been dosed in its Phase 2 combination trial of PIKTOR, which is FTH-001 (serabelisib) and FTH-003 (sapanisertib) with paclitaxel. The trial is the most advanced of its kind to investigate a novel approach of dual PI3Kɑ-mTORC1/2 inhibition targeting cancer metabolism in patients with endometrial cancer.

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