A study led by the Hospital del Mar Research Institute has established the importance of immunoglobulin A, an antibody that is part of the immune system, in generating a response to pneumonia vaccines.

Researchers have found that the absence of this antibody leads to an overgrowth of gut microbiota, triggering an excessive and sustained immune system response, which ultimately becomes exhausted and fails to respond effectively to vaccines.

The study, published in Science Advances, opens the door to exploring the possibility of early immunoglobulin therapy administration to prevent this process and reduce the risk of potentially dangerous infections, even in at-risk individuals without a diagnosed immunodeficiency

Professor JianQiao Zhou’s team at Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, has developed a latent diffusion model named CoLDiT. This model generates high-quality breast ultrasound images across different BI-RADS categories to overcome medical data sharing barriers. The study, titled “Synthetic Breast Ultrasound Images: A Study to Overcome Medical Data Sharing Barriers,” was published in the journal Research (DOI: 10.34133/research.0532).

New research from Edith Cowan University (ECU) has confirmed that erectile dysfunction in patients living with prostate cancer could be significantly improved through regular exercise.

Researchers at Washington University in St. Louis are discovering the electrochemical properties of biomolecular condensates which could help in development of cancer or ALS treatments

Canadian researchers have developed an effective new technique for identifying aggressive medulloblastoma—the most common type of malignant brain tumour in children—and potentially sparing young patients from unnecessary treatments and their harmful long-term side effects. Current diagnostic techniques rely on complex genetic tests that are expensive and only available in a handful of specialized laboratories worldwide. This research used proteomics to reveal that a protein called MYC is prominent in the most aggressive medulloblastoma cases, and developed an immunohistochemistry test for MYC that can be performed in a single day by any pathology lab around the world. Instead of waiting weeks for complex genetic tests, doctors can quickly determine which children truly need radiation and who can safely avoid it.

Ultraviolet (UV) radiation from the sun is a well-known cause of DNA damage, which can lead to diseases like skin cancer. But how do our cells repair this damage to protect us? Researchers from Sabanci University, Veysel Oğulcan Kaya and Ogün Adebali, have uncovered a fascinating answer: when DNA is damaged by UV light, our cells reorganize their genetic material in 3D space to prioritize repair, in what might be called a “cellular rescue mission.”