Early clinical trial results show that serial brain biopsies reveal immune activity in brain cancer not captured by standard scans

A multi-institutional study from the Accelerating GBM Therapies Through Serial Biopsies TeamLab, led by investigators from the Mass General Brigham Cancer Institute, found that serially testing tumor samples can help detect when a cancer treatment is activating the immune system in recurrent glioblastoma (GBM), even when traditional imaging measures cannot. Their results are published in Science Translational Medicine.  

Researchers from UC San Francisco (UCSF), have discovered that a novel combination of immunotherapies can reprogram the immune environment of colon cancer tumors that spread to the liver. In preclinical models, this therapy often eliminated tumors entirely, offering a potential new path for treating patients with advanced colorectal cancer.

A new study led by researchers from the Johns Hopkins Bloomberg School of Public Health found that older adults receiving federal housing assistance were on average diagnosed at earlier stages with three common cancers—colon, breast, and non-small cell lung—compared to peer cancer patients who were not receiving assistance.