Cell-preservation technique could make CAR-T cell therapy more accessible
Peer-Reviewed Publication
Updates every hour. Last Updated: 3-Nov-2026 22:16 ET (4-Nov-2026 03:16 GMT/UTC)
Researchers at IRB Barcelona identify a molecular mechanism that amplifies chronic inflammation in aged skin.
With age, two proteins that normally help maintain epidermal function, BMAL1 and YAP, switch to promoting genes associated with inflammation.
The study, conducted mainly in mice and supported by the analysis of human skin data, has been published in the journal Nature Aging.
Roberts has fostered collaborative, innovative partnerships across disciplines and institutions to accelerate progress against childhood cancer and other catastrophic diseases.
UC Irvine researchers highlight mitochondrial dysfunction as a promising target for reducing a serious neurological complication of CAR T-cell therapy in cancer patients.
The study outlines how existing drugs could be repurposed as safer alternatives to steroids in addressing this complication.
The research provides a road map for future clinical evaluation.
In collaboration with partners, researchers at Kaunas University of Technology (KTU) have developed new hybrid compounds that, in laboratory studies, were shown to simultaneously reduce the viability of aggressive cancer cells and inhibit the growth of certain bacteria and fungi.