Single amino acid change may help viruses jump from bat to human
Peer-Reviewed Publication
Updates every hour. Last Updated: 17-Jun-2026 17:15 ET (17-Jun-2026 21:15 GMT/UTC)
Long COVID (LC), characterized by onset of symptoms within 3 months of COVID-19, poses a major clinical challenge. This highlights the need for biomarkers to evaluate the pathophysiology of LC. In this context, researchers have analyzed the antibody titers against SARS-CoV-2 spike (S) and nucleocapsid (N) proteins in patients with LC. It was observed that N-antibody levels reflected prior infection severity, while lower S-antibody levels were linked to memory problems and poor quality of life.
The COVID-19 pandemic did not push nurses out of hospitals or other care settings as feared, but nurses left their primary jobs at nearly double the rate from 2018 to 2022, a new University of Michigan study found.
The study documents how vulnerable families in India coped with food insecurity during the pandemic. It highlights how interviewed families sometimes went without food, medicine, and other essentials to cope with the fallout of the pandemic.
A nationwide study tracking Japanese adults before, during, and after the COVID-19 pandemic found that health-related quality of life steadily declined over seven years and did not rebound after the public health emergency ended. Researchers say the decline may reflect the cumulative impact of pandemic-related changes in physical activity, mental well-being, and social interaction among working-age adults across Japan.
- A Cambridge-led team has developed a way to engineer better vaccines that could provide broad protection from thousands of variants of viruses - such as coronaviruses or Ebola - in a single vaccine.
- This represents a fundamental new vaccine technology that could prevent future pandemics before they begin.
- The team used the technology to engineer a vaccine designed to protect against a wide range of coronaviruses, including the cause of the COVID pandemic.
- The results of the first-in-human clinical trial of this technology found it is safe and well tolerated.The rise in remote work caused by the COVID-19 pandemic has substantially increased time spent alone and worsened workers’ mental health, according to a new study based on survey data from more than 500,000 Americans. In evaluating remote employees’ mental health, the analysis moves beyond the main consequence of remote work more typically evaluated in studies to date: worker productivity. The study’s results suggest that “the shift in work location to the home carries measurable costs at the population level,” Emma Zhang and Rourke O’Brien write in a related Perspective. After the pandemic led to many people working from home, the results of studies evaluating the mental health impacts on employees were mixed. To understand remote work’s effect on human well-being better, Natalia Emanuel and colleagues analyzed data from five nationally representative US-based surveys that together spanned more than a decade and included 568,000 respondents. They compared workers’ experiences before the pandemic (2011 to 2019) with experiences from the post-peak period (2022 to 2024), excluding the acute pandemic years of 2020 to 2021. The authors found that workers in jobs amenable to remote work experienced substantially larger post-pandemic increases in time spent alone, worsened mental well-being across multiple measures, and increases in the use of mental health services and prescriptions. These effects were particularly pronounced among individuals living alone. Noting a limitation of their study, the authors said, “Given that our data end in 2024, we cannot fully capture long- term adaptations among remotable workers.” If workers made changes, such as cultivating social networks outside of work, they may not yet have reaped the full benefits by the time of the study, they added. “Across a range of remote work arrangements, both individuals and organizations may want to prioritize making remote work less isolating by, for example, coordinating in-office days for hybrid workers or encouraging informal interaction, even online,” Emanuel et al. conclude.
Data is available for the creation of data visualization images. For more information, please contact Natalia Emanuel at natalia@nataliaemanuel.com
In a new study funded University of Delaware researchers from multiple disciplines assessed the challenges of the coordinated community response systems serving victims of domestic violence during the height of the COVID-19 pandemic. Through interviews with domestic violence coalition leaders, they find that the pandemic uniquely disrupted the infrastructure for service coordination, the continuity of law enforcement and legal systems, the maintenance of evidence-based practices and more.