A Viewpoint published in Genomic Psychiatry examines how Brazil's extraordinary genetic diversity creates unparalleled opportunities for longevity research. Dr. Mayana Zatz and her team describe their longitudinal ongoing study which has collected so far over 160 centenarians, including 20 supercentenarians distributed across multiple Brazilian regions. The cohort includes remarkable cases, such as Sister Inah Canabarro Lucas, who was recognized as the world’s oldest living person until her death at age 116 in April 2025, as well as the world’s oldest living man, aged 113, three supercentenarians who survived COVID-19 before vaccines were available, and families with multiple centenarian siblings. Brazil's centuries of genetic admixture may harbor protective variants invisible in more homogeneous populations.

Long COVID—defined as symptoms persisting ≥ 2 months beyond acute SARS-CoV-2 infection without alternative explanation—now affects an estimated 65 million people worldwide and lacks any approved, evidence-based therapy; the present overview therefore synthesizes current mechanistic insights and catalogs experimental interventions ranging from supervised rehabilitation to antivirals, anticoagulants, anti-inflammatories, nutraceuticals and emerging biologics.  Key pathogenic drivers include persistent viral reservoirs, chronic low-grade inflammation with IL-1β/IL-6/TNF-α elevation, micro-clot formation via spike-protein–fibrinogen interactions, auto-immunity, gut dysbiosis and mitochondrial dysfunction.  These pathways translate into multi-organ sequelae: endothelial dysfunction, myocarditis, neuro-inflammation, small-fiber neuropathy, ME/CFS-like fatigue, menstrual irregularities, glucose intolerance and renal or hepatic injury.

China has moved from patchy, post-crisis biosafety rules to a unified legal regime anchored by the 2020 Biosecurity Law, yet fragmentation, weak risk intelligence and poor inter-agency coordination still leave gaps that could be exploited by novel pathogens, synthetic biology or geopolitical tension.  Historical review shows three phases: 1949-2002 built basic disease reporting and plant-quarantine systems but relied on paper records; 2003-2019 introduced internet-based surveillance, BSL-3/4 laboratories and alignment with WHO’s International Health Regulations after the SARS shock; 2020-present elevated biosafety to national-security status, enacted the Biosecurity Law and poured funds into diagnostics, vaccines and bio-economic R&D during COVID-19.  These steps created the skeleton of a modern system, but four structural weaknesses persist: strategic plans lack operational road-maps and AI-enabled foresight; the legal framework offers no clear dispute-resolution or accountability mechanisms; organisational silos among health, agriculture, science and military agencies hamper horizontal coordination; and public awareness plus professional training remain patchy, weakening compliance culture.

Researchers from The University of Osaka found that common arguments used to encourage COVID-19 vaccination increase compliance but also intensify negative attitudes toward people with opposing views. The study highlights the need for public health communication strategies that promote vaccination while reducing social polarization.

Researchers at National University of Singapore used multiple interpretable machine learning methods to predict traffic congestion in in Alameda County in the San Francisco Bay Area, USA, during the pre-lockdown, lockdown, and post-lockdown periods.