A new study from Tulane University sheds light on ventilator-induced lung injury, a complication that gained increased attention during the COVID-19 pandemic, which led to a surge in patients requiring mechanical ventilation. The study suggests that repeated collapse and reopening of tiny alveoli—air sacs in the lungs essential for breathing—during mechanical ventilation may cause microscopic tissue damage, playing a key role in ventilator-related injuries that contribute to thousands of deaths annually.