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The fast-spreading UK, South Africa, and Brazil coronavirus variants are raising both concerns and questions about whether COVID-19 vaccines will protect against them. New work led by Bing Chen, PhD, at Boston Children's Hospital analyzed how the structure of the coronavirus spike proteins changes with the D614G mutation -- carried by all three variants -- and showed why these variants are able to spread more quickly. The team reports its findings in Science (March 16, 2020).
A new study published online in the Annals of the American Thoracic Society reveals how socioeconomic factors partially explain the increased odds that Black and Hispanic Americans have of testing positive for SARS-CoV-2, the virus that causes COVID-19.
- Annals of the American Thoracic Society
Findings of the South African study in the Oxford AstraZeneca Covid-19 vaccine trial were published in the <i>New England Journal of Medicine</i> (<i>NEJM</i>), the leading medical journal globally, on Tuesday, 16 March 2021, following peer review.
- New England Journal of Medicine
- , U.K. Research and Innovation (UKRI), Universit, U.K. National Institute for Health Research, , South African Medical Research Council Strategic Health Innovation Partnerships,
A new study uncovers which cell types can be infected by SARS-CoV-2 due to their viral entry factors. The study also suggests that increased gene expression of these viral entry factors in some individuals partially explains the differences of COVID-19 severity reported in relation to age, gender and smoking status.
- Nature Medicine