Laser technology enables magnetic liquid metal to form a multifunctional skin on 3D-printed soft robots
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Updates every hour. Last Updated: 20-Oct-2026 14:16 ET (20-Oct-2026 18:16 GMT/UTC)
A nurse-led card game may help ease children’s anxiety at a particularly stressful point in surgery—entry to the operating room—and may improve cooperation during anesthesia induction and early postoperative behavior, a single-center trial suggests.
Severe infection can leave lasting cognitive deficits, but the mechanisms are unclear. Using a mouse sepsis model and human brain tissue, researchers found that peripheral monocyte-derived macrophages enter the hippocampus during acute infection and persist for months. These long-lived cells interact with microglia through pleiotrophin signaling, enhancing phagocytic activity and contributing to chronic neuroinflammation and cognitive impairment. Early blockade of immune cell entry reduced these long-term deficits, identifying a potential intervention window.
Public biomedical databases such as NHANES, UK Biobank, FAERS, the Global Burden of Disease Study, and FinnGen have become a focus of the research-integrity debate, following a rapid rise in papers built from broadly accessible datasets. A correspondence published in Medicine Discovery argues that the quality of public database research rests on the study process, while the database name provides little information about scientific quality, and that treating a familiar database name as a marker of low quality risks confusing the infrastructure with the production model that exploits it. Citing a scientometric analysis of 36 health datasets — nine of which showed publication patterns consistent with rapid, formulaic expansion, producing 23,005 indexed publications in 2025 and an estimated excess of 11,577 publications above the prior trend — the authors argue that the same NHANES files support careful epidemiology, surveillance, and methods development as well as formulaic work, and that the recent surge emerged long after the survey architecture and its public documentation were established. They describe how generative AI has changed the economics of secondary data research, distinguishing researcher-directed assistance from more autonomous workflows that extend into question formulation and analytical planning, and warning of a plausible risk of automated hypothesis fishing. The correspondence proposes three actions for editorial policy: a short dataset-specific methods note for heavily reused resources; stronger transparency around analysis code, preregistration, and AI use; and editorial screening focused on study conduct rather than data provenance.
A research team has identified a molecular brake on the accumulation of wheat grain proteins that help determine flour processing quality.
Researchers in China developed AgriMamba, a text-guided multimodal framework for plant disease severity grading in complex field environments. The framework combines disease images with pathological descriptions of lesion color, shape, edge characteristics, and spatial distribution. It follows a coarse-to-fine process that localizes the target leaf, segments lesion regions, and quantifies disease severity using lesion-to-leaf area ratios. Experimental and visualization results showed that AgriMamba achieved competitive performance compared with several representative deep learning methods. The model also progressively focused on target leaves and lesions despite background interference, leaf occlusion, and small or scattered disease regions. These findings provide a new technical approach for automated plant disease assessment in complex field environments.
Researchers in China identified that the TraesCS4B02G044100 (TaGeBPL-4B) is a candidate gene of the GNS using QTL mapping and GWAS. Knockout and overexpression studies showed that TaGeBPL-4B participates in the positive regulation of the GNS. The RNA-seq and DAP-seq analyses revealed that TraesCS5B02G120800 (TaAAP-5B) is a direct downstream target gene of TaGeBPL-4B. We further confirmed this regulation by Y1H, Dual-Luc and EMSA. TaGeBPL-4B activates the expression of TaAAP-5B and modulates amino acid contents, which possibly influence wheat spike development and GNS.
Researchers in China functionally characterized the branching habit regulatory gene AhPILS in peanut through MutMap analysis. This gene encodes a PIN-like protein that mediates polar auxin transport, thereby establishing an auxin gradient at the base of lateral branches. The formed auxin gradient potentially promotes cell elongation, which facilitates the morphological transition of peanut lateral branches from a spreading growth habit to an upright growth habit. This study identifies a novel functional gene, reveals key insights into the molecular regulatory mechanism of peanut branching habit, and provides elite germplasm resources for the molecular breeding of peanut cultivars with ideal plant architecture.