PKU scientists reveals phenological divergence between plants and animals under climate change
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Updates every hour. Last Updated: 16-Jun-2025 16:09 ET (16-Jun-2025 20:09 GMT/UTC)
Imagine the deep frustration of countless men who long to become fathers, only to face infertility due to a genetic condition they can't control. For those with Klinefelter syndrome, this painful reality is a constant struggle.
How does an extra X chromosome lead to infertility in men? Professor Qiao Jie and her team at Peking University Third Hospital revealed why Klinefelter syndrome, a common genetic condition affecting one in every 600 men, often leads to infertility—and they’ve identified a potential way to treat it. Their research, titled “How the extra X chromosome impairs the development of male fetal germ cells,” published in Nature Cells (DOI: 10.1038/s41586-024-08104-6) provides new insights into the molecular mechanisms at play and even offers potential treatment avenues.
Researchers from Fudan University have developed an innovative glycopeptide enrichment strategy, offering a rapid and efficient tool for comprehensively profiling of glycosylation types, including N-glycosylation, O-GlcNAcylation, and O-GalNAcylation. This efficient method minimizes sample input and simplifies workflows, providing a powerful tool for studying glycosylation’s roles in biology and disease.