New pesticide formulation developed for safer and more effective pest control
Peer-Reviewed Publication
Updates every hour. Last Updated: 4-Aug-2025 21:11 ET (5-Aug-2025 01:11 GMT/UTC)
This study utilizes bibliometric analysis to investigate the research landscape of FAP-directed cancer theranostics, focusing on the development and application of radiotracers based on quinoline-based FAP inhibitors (FAPIs).
Research team led by Tao Zhang introduces CCB-RR, an innovative model for recommending code reviewers in open-source projects, achieving 87% accuracy in Top-10 recommendations and significantly outperforming baselines with a context-centric approach.
Researchers from Nantong University developed a novel targeted drug delivery system using functionalized pillararenes for multimodal synergistic cancer therapy, combining chemotherapy and photodynamic therapy to precisely attack tumor cells while sparing healthy ones.
Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal cord compression. This condition is more prevalent in Asian countries and has been associated with various genetic and hormonal factors. Recent insights reveal the potential role of interferon (IFN) signaling in the pathogenesis of OPLL, particularly the type I IFN pathway, which is known to play a role in innate immune responses and bone formation. A single-cell transcriptome profiling study has identified the activation of type I IFN signaling in ossified posterior longitudinal ligament, suggesting a therapeutic target for OPLL.
Toughening glass matrix ceramics remains a challenge due to their intrinsic brittleness, yet high-toughness ceramics are crucial for various applications, especially dental restoration. Dental glass ceramics require a toughness above 5 MPa∙m¹/² to prevent fractures and extend lifespan. The key challenge is enhancing mechanical properties without sacrificing translucency. In this study, ZrO₂-SiO₂ glass ceramics were doped with amorphous Al₂O₃ at the nanointerface and nano-domains. This modification significantly improved mechanical performance, achieving a flexural strength of 960 MPa and a toughness of 8.05 MPa∙m¹/². Despite these enhancements, the material maintained excellent translucency, demonstrating its potential for dental restoration and other structural applications.