High-efficacy adjuvanted subunit vaccine against variant infectious bursal disease virus in chicks
Peer-Reviewed Publication
Updates every hour. Last Updated: 29-Dec-2025 08:11 ET (29-Dec-2025 13:11 GMT/UTC)
A recent study demonstrates that the IBDV VP2 subunit vaccine prepared in this study was able to induce the production of specific antibodies, inhibit bursal atrophy and resist viral attack. The vaccine offers a safer alternative to traditional live-attenuated vaccines, with potential applications in global poultry disease control.
Non-suicidal self-injury (NSSI) is a significant health concern among adolescents and young adults, often resulting from adverse childhood experiences (ACEs). Dissociation, post-traumatic symptoms and attachment style may have a role in shaping such associations. This study aims to provide a unified model of the impact of ACEs on NSSI, exploring complex post-traumatic stress disorder (cPTSD) symptoms and dissociation as potential mediators and the role of the predominant attachment style in affecting such associations.
Schizophrenia is characterised by pervasive cognitive deficits that significantly impair daily functioning and quality of life. Pharmacological treatments have limited efficacy in addressing these deficits, highlighting the need for adjunctive interventions like computerised cognitive training (CCT). This study aimed to evaluate the effects of a 30-session CCT programme on mental well-being and cognitive performance in individuals with schizophrenia. Additionally, it assessed the usability and acceptability of CCT in this population.
Crystallographic engineering of Zn anodes to favor the exposure of (002) planes is an effective approach for improving stability in aqueous electrolytes. However, achieving non-epitaxial electrodeposition with a pronounced (002) texture and maintaining this orientation during extended cycling remains challenging. This study questions the prevailing notion that a single (002)-textured Zn anode inherently ensures superior stability, showing that such anodes cannot sustain their texture in ZnSO4 electrolytes. We then introduced a novel electrolyte additive, benzyltriethylammonium chloride (TEBAC), which preserves the (002) texture over prolonged cycling. Furthermore, we successfully converted commercial Zn foils into highly crystalline (002)-textured Zn without any pretreatment. Experiments and theoretical calculations revealed that the cationic TEBA+ selectively adsorbs onto the anode surface, promoting the exposure of the Zn(002) plane and suppressing dendrite formation. A critical discovery was the pitting corrosion caused by chloride ions from TEBAC, which we mitigated by anion substitution. This modification leads to a remarkable lifespan of 375 days for the Zn||Zn symmetric cells at 1 mA cm-2 and 1 mAh cm-2. Furthermore, a TEBA+-modified Zn||VO2 full cell demonstrates high specific capacity and robust cycle stability at 10.0 A g-1. These results provide valuable insights and strategies for developing long-life Zn ion batteries.
While being a promising candidate for large-scale energy storage, the current market penetration of vanadium redox flow batteries (VRFBs) is still limited by several challenges. As one of the key components in VRFBs, a membrane is employed to separate the catholyte and anolyte to prevent the vanadium ions from cross-mixing while allowing the proton conduction to maintain charge balance in the system during operation. To overcome the weakness of commercial membranes, various types of membranes, ranging from ion exchange membranes with diverse functional groups to non-ionic porous membranes, have been designed and reported to achieve higher ionic conductivity while maintaining low vanadium ion permeability, thus enhancing efficiency. In addition, besides overall efficiency, stability and cost-effectiveness of the membrane are also critical aspects that determine the practical applicability of the membranes and thus VRFBs. In this article, we have offered comprehensive insights into the mechanism of ion transportation in membranes of VRFBs that contribute to the challenges and issues of VRFB applications. We have further discussed optimal strategies for solving the trade-off between the membrane efficiency and its durability in VRFB applications. The development of state-of-the-art membranes through various material and structure engineering is demonstrated to reveal the relationship of properties-structure-performance.
Researchers have launched a new open-source MATLAB toolbox that generates synthetic networks with built-in vital nodes, providing a standardized benchmark for accurate influential-node detection in epidemic control, power-grid resilience, and social media analysis.
A new open-source modular mobile manipulator platform streamlines embodied AI research with unified simulation-to-reality APIs, plug-and-play modules, and a turnkey PyBullet framework to accelerate service robot deployment in healthcare, manufacturing, logistics, and home assistance.
Renmin University researchers present a comprehensive survey of sampling- and sketch-based algorithms for distinct value estimation in big data, offering insights to accelerate database queries, enhance network security anomaly detection, and reduce cloud analytics costs.
Researchers unveil a new Python-based assertion verification framework for agile hardware design, enabling real-time error detection with minimal area and performance overhead to streamline prototyping and boost reliability.
This study provides valuable insights into the prevention of toxic gas diffusion during lithium battery fires, offering a potential solution for protecting firefighters’ respiratory health. The findings highlight the potential of flower-like CeO2 microspheres as an effective adsorbent for HF gas removal during LIB thermal runaway, which could significantly enhance the safety of lithium-ion batteries in various applications.