EurekAlert! China News - News Releases from China

News from China

Updates every hour. Last Updated: 28-Jun-2025 23:10 ET (29-Jun-2025 03:10 GMT/UTC)

DHHC5 regulates intestinal lipid absorption and lymphatic function

Higher Education Press
Peer-Reviewed Publication

The study reveals that DHHC5 is essential for the proper function of lacteals. DHHC5 mediates the palmitoylation of CRYBG1, an actin-binding protein, thereby regulating the localization of VEGFR2 in lipid rafts of lymphatic endothelial cells (LECs). This process is crucial for the formation of “button-like” junctions between LECs that allow chylomicrons to enter lacteals.

Journal: Life Metabolism
Funder: National Natural Science Foundation of China, National Key Research and Development Program of China, Shanghai Basic Research Field Project “Science and Technology Innovation Action Plan”

New cell sorting strategy enhances stem cell purity for cultured meat production

Maximum Academic Press
Peer-Reviewed Publication

A research team has developed a novel strategy for isolating high-purity muscle stem cells (MuSCs), fibro-adipogenic progenitors (FAPs), and smooth muscle cells (SMCs) from porcine muscle tissue.

Journal: Food Materials Research

New insights into esophageal cancer through metabolomics and microbiomics approaches

Shanghai Jiao Tong University Journal Center
Peer-Reviewed Publication

Esophageal cancer is a prevalent and aggressive malignancy associated with a poor prognosis. Metabolomics and microbiomics have emerged as promising approaches for investigating the tumor microenvironment and monitoring dynamic changes throughout the treatment process. These methodologies facilitate the direct observation of phenotypic alterations with high sensitivity, throughput, and adaptability across diverse sample types. Microbial genomic data play a crucial role in predicting the metabolic potential of microorganisms, whereas metabolomics offers direct evidence of active metabolic pathways under specific conditions. This review presents novel insights into the pathogenesis, diagnosis, and treatment of esophageal cancer through the application of metabolomics and microbiomics. Future advancements in the integration of multi-omics data are expected to further elucidate the metabolic mechanisms and pathophysiological processes underlying esophageal cancer, thereby laying a robust scientific foundation for early diagnosis, prognostic assessment, and personalized treatment strategies.

Journal: LabMed Discovery

Egg white hydrolysates show promise as natural antihypertensive agents in hypertension management

Maximum Academic Press

A research team reveals the promising antihypertensive effects of egg white hydrolysates (EWH) and ovotransferrin-depleted egg white hydrolysates (OD-EWH) in spontaneously hypertensive rats (SHRs), suggesting that these natural ingredients could be effective alternatives to traditional pharmaceuticals for managing hypertension.

Journal: Food Materials Research

Living hydrogel-based miniaturized and portable bio-battery developed for precise nerve stimulation

Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences
Peer-Reviewed Publication

SIAT's researchers develop a miniaturized, portable bio-battery, which enables the precise control over bioelectrical stimulation and physiological blood pressure signals.

Journal: Advanced Materials

An enzyme-proof glycan glue for extracellular matrix to ameliorate intervertebral disc degeneration

Nanjing University School of Life Sciences
Peer-Reviewed Publication

A collaborative team from the University of Macau and Nanjing University found, using clinical databases and samples, that the loss of a protein named MFG-E8 in nucleus pulposus (NP) tissue is a factor in intervertebral disc degeneration (IDD), the leading cause of back pain worldwide. They suspected that MFG-E8 is bound to the glycan matrix in the NP tissue, but increasing the enzymes during IDD cleaves the glycans, releasing MFG-E8 and affecting the cell phenotype. Accordingly, they devised a glycan molecule, called GMOC, that is similar to the native glycan matrix but escapes the cleavage from enzymes that cleave the native glycans. They injected GMOC into rat and rabbit models of IDD and observed amelioration of symptoms, providing new insights for developing therapeutic strategies for future IDD treatment. The study was recently published in Nature Communications (https://rdcu.be/ejPlG).

Journal: Nature Communications
Funder: Science and Technology Development Fund, Macao SAR, National Science Foundation of China, Jiangsu Provincial Science and Technology Plan Special Fund, University of Macau

Revolutionary algorithm optimizes nuclear reactor radiation shielding design

Nuclear Science and Techniques
Peer-Reviewed Publication

The research team (NEAL) at the University of South China has proposed an innovative radiation-shielding optimization method based on a reference-point-selection strategy. This method has been successfully applied to the optimization of radiation-shielding designs for nuclear reactors. By integrating genetic algorithms with artificial bee colony algorithms, the method substantially improves the lightweight, compact, and radiation protection performance of shielding structures, thereby providing vital technical support for the design of nuclear reactors.The research team (NEAL) at the University of South China has proposed an innovative radiation-shielding optimization method based on a reference-point-selection strategy. This method has been successfully applied to the optimization of radiation-shielding designs for nuclear reactors. By integrating genetic algorithms with artificial bee colony algorithms, the method substantially improves the lightweight, compact, and radiation protection performance of shielding structures, thereby providing vital technical support for the design of nuclear reactors.

Journal: Nuclear Science and Techniques

From lab to body: nanofluidic patch offers new hope for chronic diseases

Peking University
Peer-Reviewed Publication

Peking University, May 16, 2025: A research team led by Professor Li Mo at Peking University Third Hospital has developed a revolutionary battery-free, flexible NanoFLUID patch for precise drug and gene delivery to internal organs. Their study, titled "A battery-free nanofluidic intracellular delivery patch for internal organs," was published in Nature, marking a breakthrough that overcomes key biological barriers. The technology enables highly efficient, low-toxicity intracellular therapy with single-cell precision, integrating medicine, engineering, and chemistry to advance targeted treatments for severe diseases.

Journal: Nature

Scientists develop innovative aerosol system to build asymmetric superstructures

Hefei Institutes of Physical Science, Chinese Academy of Sciences
Peer-Reviewed Publication

A research team from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, together with collaborators at the University of California, has developed a novel aerosol-based emulsion system that enables the self-assembly of asymmetric nanostructures—something long considered a major challenge in materials science.

Journal: Advanced Materials

Enhanced CsPbBr3 x-ray detectors achieve record-low detection limits

Hefei Institutes of Physical Science, Chinese Academy of Sciences
Peer-Reviewed Publication

In a major step forward for radiation detection, a research team led by Prof. MENG Gang has significantly enhanced the performance of CsPbBr₃-based X-ray detectors by dramatically lowering their detection limit and suppressing noise and ion migration through innovative cooling and defect-passivation strategies.

Journal: Advanced Functional Materials

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