Clinician gender and agreement with intensive care unit recommendations for patients aged 80 and over
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Updates every hour. Last Updated: 26-Oct-2026 15:16 ET (26-Oct-2026 19:16 GMT/UTC)
In a paper published in Earth and Planetary Physics,a research team of seismologists explores strong earthquake hazards along major active faults on the western Ordos margin using multiple seismological methods. The sparse earthquake segments overlapping low b-value anomalies mark stress-loaded locked fault patches, interpreted as potential seismogenic asperities. Theoretical magnitudes estimated from the spatial extents of these sparse segments along the faults are broadly consistent with the magnitude range of historical strong earthquakes.
This collection features articles on Supramoleular Interactions published in Supramolecular Materials. All articles are free to read and download.
A Peking University team has automated cataract screening from routine IOL Master 700 scans. Their "lens average density" biomarker achieved an AUC of 0.975 and correlated strongly with the clinical LOCS III standard (ρ = 0.804). The study revealed that highly myopic eyes (axial length ≥26 mm) carry a distinct nuclear cataract signature—83% prevalence versus 40% in normal-length eyes—emerging roughly 12 years earlier. The approach could embed early screening into existing workflows without extra patient burden.
Cancer immunotherapy offers long-term remissions but struggles with primary resistance, complex progression, and severe side effects. A landmark review in Science Bulletin highlights how multimodal AI integrates multi-scale data—from spatial omics and pathology to imaging and health records—to transform patient stratification. Tracing AI's evolution into foundation models and "virtual cells," the authors outline a clinical roadmap balancing efficacy, toxicity, and disease dynamics.
Highlights
• Homoharringtonine (HHT) downregulates CCAAT/enhancer-binding protein alpha (CEBPA) expression.
• The homoharringtonine, daunorubicin, and cytarabine (HAD) induction regimen demonstrates efficacy in acute myeloid leukemia (AML) with CEBPA double mutations (CEBPAdm).
• The HAD regimen produces encouraging event-free survival (EFS) and relapse-free survival (RFS) in patients with CEBPAdm AML, both of which met the predetermined objectives.
Highlights
• Single-cell analysis defines the adverse diffuse large B-cell lymphoma tumor microenvironment (DLBCL TME) as a state of classical T-cell exhaustion rather than immune quiescence.
• A robust five-gene score (immune exhaustion-Related Prognostic Score, IERPS) independently predicts poor survival across multiple cohorts.
• IERPS exhibits clinical significance in individualized medicine for chimeric antigen receptor (CAR)-T cell therapy.
• IERPS dynamically tracks clinical response to the T-cell engager glofitamab.
Long-term fertilization enhances most functional groups. Manure and manure+NPK surpass NPK in enriching food web components. Manure and manure+NPK surpass NPK in enriching food web components. Manure and manure+NPK surpass NPK in enriching food web components.
A novel OsSBEIIb allele was identified in an indica rice mutant. The OsSBEIIb mutation increases the resistant starch (RS) content in raw rice flour, as well as in retrograded and heated rice. The chalk2 mutant serves as a valuable indica rice germplasm for breeding high-RS rice varieties.