Millions of men could benefit from faster scan to diagnose prostate cancer
Peer-Reviewed Publication
Updates every hour. Last Updated: 21-Sep-2025 08:11 ET (21-Sep-2025 12:11 GMT/UTC)
A quicker, cheaper MRI scan was just as accurate at diagnosing prostate cancer as the current 30-40 minute scan and should be rolled out to make MRI scans more accessible to men who need one, according to clinical trial results led by UCL, UCLH and the University of Birmingham.
A consortium led by the University of Southampton has received funding to develop next-generation treatments for cancer and chronic inflammation.
A major UK study, led by researchers at the University of Oxford’s Nuffield Department of Primary Care Health Sciences, Oxford University Hospitals NHS Foundation Trust, the National Institute for Health and Care Research (NIHR) Oxford Biomedical Research Centre, and Oxford Cancer, has provided the most comprehensive analysis to date of a cancer diagnosis pathway for patients presenting with non-specific symptoms (NSS), such as unexplained weight loss or fatigue. These symptoms can indicate a wide range of conditions, from benign diseases to late-stage cancers, making timely and accurate diagnosis a significant challenge in primary care.
To improve treatment rates for these patients, UCSF researchers designed a CAR T cell therapy and combined it with an older class of diabetes drugs called thiazolidinediones, to enhance NECTIN4 expression and make tumor cells more susceptible to NECTIN4-CAR T therapy.
Researchers from the National University of Singapore and the National Cancer Centre Singapore have developed a hydrogel-based method to keep human lymph node tissue alive and functional outside the body for at least a week — significantly longer than existing approaches. By embedding tissue slices in a bioengineered gel that mimics the body’s natural environment, the system preserves the structure and immune functions of the lymph node, allowing scientists to observe real-time responses to cancer antigens and mRNA vaccines. The platform offers a more accurate and human-relevant alternative to preclinical models and could support the development of personalised immunotherapies and vaccines.