Innovation Center of NanoMedicine (iCONM), in collaboration with Prof. Takahiro Nomoto's Lab at the University of Tokyo, will hold a seminar on drug design and rationalization of treatment protocols for photodynamic therapy (PDT) based on singlet oxygen imaging on September 19, at 1:30 pm. This is based on a Japan-Germany Bilateral Collaboration Research between DAAD (German Academic Exchange Service) and JSPS (Japan Society for the Promotion of Science), with the aim of expanding the framework for joint research on the topic PDT and stimulating its international collaboration.

The University of Cincinnati Cancer Center's Annabelle Anandappa, MD, has received the ASCO Conquer Cancer Women Leaders in Oncology Endowed Young Investigator Award and a Damon Runyon Physician-Scientist Training Award to support preclinical research on the use of RAS inhibitors to treat acute myeloid leukemia (AML).

While antioxidants generally promote health, researchers have learned that under certain conditions some antioxidants operating within cellular compartments can fuel the spread of cancer. New work demonstrates how one antioxidant inside particular cellular compartments, the mitochondrial metabolite glutathione, helps cancer cells metastasize throughout the body by enabling their survival under low-oxygen conditions. These findings suggest that therapies capable of blocking glutathione transport into organelles within the cell could help treat breast cancer.

A team of scientists at the Garvan Institute of Medical Research has discovered that inactivation of a stress pathway makes ER+ breast cancer cells ignore stress signals, allowing them to evade treatment.