Postdoctoral researcher Dr. Mateus Vidigal de Castro at the University of São Paulo studies induced pluripotent stem cells from centenarians who survived COVID-19. His work contributes to understanding the cellular mechanisms behind exceptional longevity and disease resilience, offering potential insights for healthy aging strategies.

This multicenter study investigates the association between hydroxychloroquine (HCQ) dosage and COVID-19 mortality among hospitalized patients in China, aiming to clarify conflicting evidence from prior research. Leveraging data from multiple medical centers, the analysis focuses on determining whether low-dose HCQ confers mortality benefits with acceptable safety, contrasting with potential risks of higher doses. By systematically evaluating clinical outcomes across different HCQ dosage groups, the research seeks to provide evidence-informed guidance for antiviral therapy in COVID-19 management, particularly in resource-constrained settings.

In a study published in National Science Review, researchers present multiple lines of observational and modeling evidence for a ~4% decline in global atmospheric oxidation capacity in 2020, reflected by a drop in hydroxyl radical (OH) concentrations. Using satellite-based carbon monoxide data, as well as methane and methyl chloroform observations, the study reveals that this OH reduction occurred in both hemispheres—approximately 2.4% in the Northern Hemisphere and 5.7% in the Southern Hemisphere—driven by distinct mechanisms. In the Northern Hemisphere, reduced NO_x emissions due to COVID-19 lockdowns led to lower OH and tropospheric ozone levels, while in the Southern Hemisphere, massive emissions of reactive carbon from unprecedented Australian wildfires caused OH depletion but tropospheric ozone increases. This contrast in tropospheric ozone anomalies is further corroborated by satellite data. The findings help explain one of the record-breaking rises in atmospheric methane in 2020 and underscore the critical role of both natural and anthropogenic factors in shaping Earth’s atmospheric chemistry and global methane budget.

People who have survived cancer as children are at higher risk of developing severe COVID-19, even decades after their diagnosis. This is shown by a new study from Karolinska Institutet published in the journal The Lancet Regional Health – Europe.

A new study challenges the belief in a universal “pet effect” on human well-being. Using data collected during COVID-19 lockdowns, researchers found no significant change in respondents' well-being when they acquired or lost a pet in their household. The findings suggest that, even during a time of extreme isolation, human-animal bonds may not be as emotionally transformative as we like to believe.

Dr. Danielle Beckman's innovative research at the California National Primate Research Center demonstrates how viral infections disrupt brain homeostasis, leading to neuroinflammation and cognitive decline. Her work provides crucial insights for developing treatments for Long COVID and neurodegenerative diseases affecting millions worldwide.