Atherosclerosis, a disease characterized by the accumulation of lipids and inflammatory cells in the arterial wall, is a significant cause of cardiovascular events. A key process in atherosclerosis is the endothelial-to-mesenchymal transition (EndMT), which involves the transformation of endothelial cells into mesenchymal cells, contributing to plaque formation and vascular dysfunction. The novel anthraquinone compound Kanglexin (KLX) has been investigated for its potential to prevent EndMT in atherosclerosis by targeting the fibroblast growth factor receptor 1 (FGFR1) and suppressing the integrin β1/transforming growth factor-beta (TGFβ) signaling pathway. This study provides insights into the molecular mechanisms underlying the protective effects of KLX against EndMT and atherosclerotic progression.

A new study led by CAS Institute of Atmospheric Physics investigates the paradox of these record-breaking cold spells and assesses future risks in a changing climate. The study reveals that human-induced climate change is actually weakening extreme cold events but also highlights that while extreme cold events are becoming less common, they have not disappeared entirely.

Scientists led by Prof. LIU Jing from the Technical Institute of Physics and Chemistry of the Chinese Academy of Sciences have created a leukocyte-like liquid metallic entity that vividly simulates various leukocyte behaviors in nature.

A new study published in Advances in Atmospheric Sciences explores how machine learning and statistical techniques can refine forecasts of photovoltaic by correcting errors in weather models.

A research team led by Prof. WANG Min from the Institute of Vertebrate Paleontology and Paleoanthropology of the Chinese Academy of Sciences has discovered two bird fossils in Jurassic-era rocks from Fujian Province in southeast China. These rocks date back approximately 149 million years. The fossils fill a spatiotemporal gap in the early evolutionary history of birds and provide the evidence yet that birds were diversified by the end of the Jurassic period.

Scientists from Prof. XIE Qi's lab at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences identified two key genes and the strategy in sorghum's resistance to Striga.

A comprehensive seven-year study across 20 Chinese provinces has revealed a concerning rise in antimicrobial resistance (AMR) among diarrheagenic Escherichia coli (E. coli), a major foodborne pathogen.

Researchers explored Mendelian randomization to identify novel drug targets for metabolic dysfunction-associated steatotic liver disease (MASLD). This approach could revolutionize therapies for a condition affecting over one-third of adults globally.

Data-driven networks influence convective-scale ensemble weather forecasts