News from China
Updates every hour. Last Updated: 22-Dec-2025 05:11 ET (22-Dec-2025 10:11 GMT/UTC)
Decoding the firmness: Genetic clues to better blueberries
Nanjing Agricultural University The Academy of Science- Journal
- Horticulture Research
Not just ripening: How ethylene shapes fruits from flower to final form
Nanjing Agricultural University The Academy of Science- Journal
- Horticulture Research
From hand to machine: Making muscadines harvest-ready through science
Nanjing Agricultural University The Academy of Science- Journal
- Horticulture Research
Lost in time, found in bacteria: tracing the roots of plant terpene genes
Nanjing Agricultural University The Academy of Science- Journal
- Horticulture Research
10-km passive drone single-photon feature imaging
Light Publishing Center, Changchun Institute of Optics, Fine Mechanics And Physics, CASPeer-Reviewed Publication
- Funder
- Shanxi Province Science and Technology Major Special Project, National Natural Science Foundation of China, China Postdoctoral Science Foundation, National Key Research and Development Program of China, Shanxi Province Science and Technology Innovation Talent Team, Science and Technology Cooperation Project of Shanxi Province, Shanxi “1331 Project”, 111 projects
Slicing and dictionaries: a new approach to medical big data
FAR Publishing LimitedPeer-Reviewed Publication
With the exponential expansion of medical databases, the number of records in a single file has reached hundreds of millions, and the number of variables has increased significantly (such as the MIMIC database and the 4,484 variables in the ELSA survey). Traditional SQL queries and distributed storage systems are difficult to meet the needs of ordinary researchers due to their high technical barriers and high maintenance costs. This study proposes an innovative "slicing + dictionary" data processing strategy: by designing a multi-level slicing scheme for clinical dimensions, event dimensions, and mixed dimensions, massive datasets are decomposed into manageable subsets; at the same time, a standardized dictionary system with an encoding-description-location-attribute structure is constructed to achieve precise mapping between clinical concepts and data locations. Experimental verification shows that this method significantly reduces computational resource consumption, improves query efficiency, and supports flexible customization, enabling ordinary computing devices to load and process large-scale data on demand, which opens up new avenues for the popularization of medical big data utilization.
Hidden contamination in DNA extraction kits threatens accuracy of global zoonotic surveillance
FAR Publishing LimitedPeer-Reviewed Publication
Researchers have uncovered that silica membranes in common nucleic acid extraction kits can carry parvoviruses, causing false virus–host links in metagenomic studies and undermining emerging disease surveillance. Leveraging AI and big data, they built the PVDDC and ParvoDB to trace and correct such errors.
AI revolution in medicine: how large language models are transforming drug development
FAR Publishing LimitedPeer-Reviewed Publication
Large language models (LLMs) are revolutionizing drug development. Researchers from China are exploring the applications of LLMs in the drug development process, including target identification and drug screening, drug molecular design and optimization, drug repurposing, preclinical research, and clinical trials. Moreover, they deeply explore the major challenges LLMs face in pharmaceutical development and provide a scientific outlook on future research directions.
- Journal
- Current Molecular Pharmacology
Tumor electrophysiology in precision tumor therapy
FAR Publishing LimitedPeer-Reviewed Publication
Abnormalities in tumor electrophysiology are key drivers of malignant tumor progression. This review systematically elaborates on its molecular mechanisms and clinical translation: Tumor cells regulate proliferation, maintenance of stemness, and metastasis through membrane potential depolarization and remodeling of specific "ion channel fingerprints". These electrophysiological characteristics interact with key signaling pathways to form a complex regulatory network (e.g., TRPV1 exhibits tissue-specific regulatory patterns in different tumors). Based on the above mechanisms, targeted ion channel modulators, therapeutic tumor electric fields, and nanodelivery platforms have shown significant efficacy in preclinical and clinical studies. Especially when combined with immunomodulatory strategies, they can reshape the tumor microenvironment and enhance anti-tumor immunity. Despite challenges such as treatment-related complications and the need to verify long-term efficacy, electrophysiology-targeted therapies still provide a highly promising new direction for precision oncology.