A global registry study of 1,762 patients with hereditary transthyretin amyloidosis (ATTRv), led by Professor Henryk Wilczek and colleagues from Karolinska Institutet and published in eGastroenterology, shows that pre-transplant phenotype strongly influences long-term outcomes after liver transplantation. Cardiac involvement predicts significantly worse survival, while renal involvement alone does not. Median survival reached 20.4 years overall but dropped to 15.2 years in cardiac phenotypes. Early autonomic neuropathy progression may signal disease recurrence. These findings refine patient selection and provide a benchmark for evaluating modern disease-modifying therapies.

Plants carry their own alarm system. When cells are damaged by pathogens, small signaling molecules can alert surrounding tissues and switch on immune defenses. A new study shows that two pear-derived plant elicitor peptides (Peps), PbePep4 and PdrPep6, can strengthen resista

Soil salinization is becoming a major constraint on crop production, especially where salt and alkaline stress strike together.

A new genome-based study has revealed how geographic dispersal reshaped the genetic diversity and key traits of Crotalaria pallida, a tropical legume valued for agriculture and medicine.

Purple leaves give ornamental trees their seasonal appeal, but in some cultivars this striking color does not last. 

Rising atmospheric carbon dioxide can boost plant growth, but this benefit depends strongly on how much nitrogen is available.