Chronic wounds, particularly those in diabetic patients, present major therapeutic challenges due to impaired tissue regeneration and extracellular matrix (ECM) dysregulation. 

A recent study has developed a novel composite aerogel scaffold designed to enhance bone regeneration in cases of bone defects.

Exosomes are reshaping how scientists understand cancer progression and immune evasion. This review explores how tumor-derived exosomes orchestrate both pro-tumorigenic signaling and immune modulation within the tumor microenvironment. By highlighting their role in carrying oncogenic RNAs, reprogramming immune cells, and enabling therapy resistance, the authors present exosomes as emerging biomarkers and therapeutic vectors in the evolving landscape of cancer diagnosis and treatment.

In an era where renewable energy is rapidly transforming our power grids, solar photovoltaic (PV) systems face a persistent challenge: the sun doesn't always shine when we need electricity most. Researchers at Aalborg University have developed an innovative solution that could significantly advance how we store and manage solar energy, making renewable power more reliable and cost-effective.

In the rapidly evolving landscape of electric vehicles (EVs) and large-scale energy storage systems, accurate battery management remains a critical challenge. The state-of-charge (SOC) estimation—essentially how much "fuel" is left in your battery—has long been a complex engineering problem due to the dynamic nature of battery behavior under various conditions. Traditional methods often struggle with initial errors, cumulative inaccuracies, and sparse data collection scenarios, limiting their real-world applicability. This groundbreaking research introduces a novel approach that combines the gas-liquid dynamics model (GLDM) with an advanced filtering algorithm to overcome these persistent challenges.

Scientists have discovered that licorice extract, a common traditional herb, offers powerful protection against Paraclostridium bifermentans spores—a heat-resistant microbe that threatens the safety and shelf life of ready-to-eat (RTE) chicken breast. In laboratory tests, licorice extract concentrations above 12.5 mg/mL significantly suppressed spore growth, while a 50 mg/mL dose nearly doubled product shelf life at 15 and 20 °C. Predictive modeling confirmed the extract’s impact on microbial growth rates and lag phases. Moreover, treated chicken samples showed slower spoilage, with lower acidity and chemical breakdown. The findings open up new possibilities for natural, plant-based preservation strategies in the meat industry.

The updated European guidelines for managing metabolic dysfunction-associated steatotic liver disease (MASLD) mark a significant shift in hepatology practice. Jointly issued by the EASL, EASD, and EASO, the recommendations introduce refined disease definitions, including MASLD and MetALD, and emphasize risk-based screening, non-invasive diagnostics, and multidisciplinary care. Lifestyle interventions remain central, while new pharmacological options—especially incretin mimetics and resmetirom—are emerging for MASH with fibrosis. These comprehensive guidelines reflect progress in MASLD research, offering clinicians a structured roadmap for diagnosis, monitoring, and management tailored to both hepatic and cardiometabolic risk profiles.

Shrimp processing waste, often discarded as low-value by-product, may hold untapped therapeutic potential. In a recent study, researchers identified five antioxidant peptides from shrimp by-products, with HFVPVYEGF and EGYPFNPLL showing the most potent protective effects against oxidative damage. These peptides demonstrated the ability to reduce reactive oxygen species (ROS), boost antioxidant enzyme activity, and significantly enhance the viability of human liver cells (HepG2) under oxidative stress. The findings reveal a promising avenue for converting seafood waste into high-value bioactive ingredients with health-promoting functions.