This study proposes a one-step hydrothermal method to fabricate intergrowth Bi₇Ti₄NbO₂₁ with high ferroelectric polarization. The interlayer lattice mismatch and periodic mechanical stress lead to increased tilting along the a-axis and rotation angle in the a-b plane of Ti/NbO₆ octahedra within perovskite-like layers, serving as the main reason for increased polarization compared to the parent phase. Notably, Bi₇Ti₄NbO₂₁ exhibits excellent piezo-photocatalytic CO₂ reduction activity, with impressive CO generation rate of 426.97 µmol g⁻¹ h⁻¹.

Immunodeficiency disorders linked to cytoskeleton defects are rare and complex, often presenting with diverse clinical features. This case report highlights a patient with recurrent eosinophilia and a novel homozygous ARPC1B mutation, expanding our understanding of genetic factors in immune-related conditions.

Lung cancers with SMARCA4 deficiency are rare, typically showing aggressive behavior and poor prognosis. These tumors rarely harbor common targetable oncogenes like EGFR, ALK, or ROS1. This case report details a nonsmoking middle-aged woman with SMARCA4-deficient non-small cell lung cancer (NSCLC) and rare EGFR mutations who achieved significant tumor response with afatinib.

Polycystic ovary syndrome (PCOS) represents a significant health concern for women of reproductive age, manifesting as a complex endocrine disorder with diverse clinical presentations. Characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology, PCOS affects 5% to 20% of women and stands as a leading cause of anovulatory infertility. The pathophysiology of PCOS involves abnormal folliculogenesis, resulting in arrested follicular development and the accumulation of small antral follicles. This follicular arrest is accompanied by mitochondrial dysfunction and oxidative stress, contributing to poor oocyte quality and developmental potential. Recent research has highlighted the potential role of neurotensin (NTS), a gut-brain peptide, in the regulation of ovulation and its dysfunction in PCOS.

Atopic dermatitis (AD) is a chronic inflammatory skin disease with high prevalence, especially in children. Current treatments like topical glucocorticoids have limitations due to side effects and resistance. Traditional Chinese medicine (TCM) offers alternative solutions, with Qin-Zhu-Liang-Xue (QZLX) decoction showing efficacy in AD treatment. This study explores the mechanisms of QZLX using network pharmacology and evaluates its clinical effects through trials and animal experiments.

Ovarian cancer, a leading cause of death among gynecological malignancies, has a poor prognosis and low 5-year survival rate, necessitating new therapeutic strategies. CDK4/6 inhibitors show promise but their efficacy varies, highlighting the need for biomarkers. This study explores TRIM4's role in ovarian cancer's response to CDK4/6 inhibitors, revealing that TRIM4, an E3 ligase, influences sensitivity by modulating hnRNPDL and CDKN2C levels.

This study explores the protective effects of trigonelline against spinal cord injury in rats.

The mechanism of radiosensitizing effect of Semen podocarpi extract on CNE-2R cells is explored.

The joint team from Nankai University and Peking University has proposed a novel approach using annealing-driven reassembly of micro-bubbles to engineer controllable artificial potential landscapes in atomically thin semiconductors. This technique facilitates active spatiotemporal control of exciton dynamics at room temperature, opening new avenues for high-performance sensing, energy harvesting, and quantum information processing.