Laser-Driven micro-pinch breakthrough: Unlocking ultra-intense neutron sources
Peer-Reviewed Publication
Updates every hour. Last Updated: 29-Jun-2025 12:10 ET (29-Jun-2025 16:10 GMT/UTC)
A new Microelectromechanical system (MEMS) grating modulator has been developed, offering significant advancements in optical efficiency and scalability for communication systems.
Bismuth layer-structured ferroelectrics (BLSFs) have become the preferred high-temperature piezoelectric ceramics due to their elevated Curie temperature (TC) and environmental friendliness. Bi4Ti3O12 (BIT) exhibits a remarkable TC of 675 °C, demonstrating promising potential for high-temperature device applications. However, oxygen vacancies generated during sintering degrade piezoelectric activity. To address this limitation, an A/B-site co-doping strategy was employed to reduce oxygen vacancy concentration and enhance comprehensive electrical properties. Results reveal that introducing A-site substituents with ionic radii comparable to Bi3+ based on non-equivalent B-site doping simultaneously improves piezoelectric performance while maintaining high TC.
Researchers have created a comprehensive spatiotemporal atlas of the developing mouse lung, providing unprecedented insights into the molecular and cellular processes that shape this vital organ. The study, published in Science Bulletin, offers a detailed map of gene expression across different stages of lung development, from embryonic day 12.5 (E12.5) to postnatal day 0 (P0).
A recent study published in Medcomm-Oncology highlights the pivotal role of the enzyme alcohol dehydrogenase 4 (ADH4) in suppressing hepatocellular carcinoma (HCC) progression. This inhibition is achieved through the facilitation of retinoic acid (RA) production and the disruption of Wnt/β-cantenin pathway. The researchers further demonstrated that the combination of RA with cisplatin markedly attenuates tumor growth in mouse models, presenting a promising therapeutic strategy for advanced HCC.
Scientists have unveiled the magnesium-bound crystal structure of Akkermansia muciniphila sialidase Amuc_1547, a key enzyme enabling gut bacteria to degrade protective mucins. The study reveals a unique metal-binding pocket, a carbohydrate-binding domain, and an unconventional catalytic mechanism. These findings advance understanding of gut microbiota adaptation and offer potential pathways for therapies targeting metabolic diseases linked to mucin metabolism.