Controllable ultrahigh-affinity molecular recognition explained through ‘molecular velcro’
Peer-Reviewed Publication
Updates every hour. Last Updated: 28-Jun-2025 06:10 ET (28-Jun-2025 10:10 GMT/UTC)
Mononuclear macrophages serve as the primary target cells for the in vivo metabolism of iron-based nanomaterials. The uptake of nanoparticles by mononuclear macrophages is influenced by various factors, such as particle size, surface charge, and administration route, which subsequently affect the metabolic process. During this process, iron-based magnetic nanomaterials can induce macrophage reprogramming and participate in immune modulation. This is primarily reflected in their regulation of macrophage function through enzyme-like activities, intracellular iron metabolism, cell signaling pathways, mitochondrial energy metabolism, and responses to magnetic fields.
A research paper by scientists at Beijing Institute of Technology presented a steering control strategy for cyborg insects in operant learning training of cockroaches in a T-maze. Cockroaches developed a preference for specific maze channels after only five consecutive sessions of unilateral cercus electrical stimulation and steering behavior induction, achieving a memory score of 83.5%, outperforming traditional punishing training schemes.
A research team led by Prof. YAN Ya from the Shanghai Institute of Ceramics of the Chinese Academy of Sciences, in collaboration with scientists from Huazhong University of Science and Technology, Shanghai Jiao Tong University, and the University of Auckland, has developed a highly stable and efficient water oxidation catalyst, marking a major advancement in the field of green hydrogen production via water splitting technology.
Researchers from Sun Yat-sen University (SYSU) and the Institute of High Energy Physics (IHEP) have developed a novel top veto tracker system for the Taishan Antineutrino Observatory (TAO) experiment. Comprising 160 plastic scintillator (PS) modules with optimized wavelength shifting fiber (WLS-fiber) arrangements and silicon photomultipliers, the system offers enhanced light yield and muon detection efficiency.
A research article published by the Shanghai University presented a novel microfluidic chip design with a 3-layer configuration that utilizes a polycarbonate (PC) porous membrane to separate the culture fluid channels from the tissue chambers, featuring flexibly designable multitissue chambers. PC porous membranes act as the capillary in the vertical direction, enabling precise hydrogel patterning and successfully constructing a microfluidic environment suitable for microvascular tissue growth.
Time- and angle-resolved photoemission spectroscopy investigations discovered the fluctuating lattice-driven charge density waves at temperatures far above its transition temperature and reveal new insights into the formation mechanism of charge density waves in kagome superconductors KV₃Sb₅.