Revealing the key player in oral submucous fibrosis: Could COMP be the solution?
Peer-Reviewed Publication
Updates every hour. Last Updated: 28-Jun-2025 08:10 ET (28-Jun-2025 12:10 GMT/UTC)
A research paper by scientists at Beijing Institute of Technology presented a CFD simulation method based on biological experimental data to analyze the aerodynamic performance of pigeons during takeoff, leveling flight, and landing in free flight.
A recent study has revealed that KIAA1199, a secreted protein produced by bone marrow cells, plays a crucial role in regulating both fat formation and overall energy metabolism.
Novel cancer therapy combining multi-hydroxylated fullerene (MF) nanoparticles and mTOR inhibitors triggers organelle cascade collapse in tumors, disrupting cancer cells' self-repair capacity. By synchronizing the membrane-breaking effect of MF with dual autophagy regulation, this strategy induces lysosomal rupture, mitochondrial dysfunction, and endoplasmic reticulum stress while paralyzing cellular cleanup systems. Animal studies demonstrate potent tumor suppression and high safety, leveraging cancer cells' fragile organelle networks against them. The breakthrough establishes organelle communication disruption as a new anticancer paradigm, pioneering material science-enabled therapies independent of genetic targets.
Wuhan, China - A research team led by Professor Mingqiu Dai from Huazhong Agricultural University published a study titled "Natural variations in ZmCCT2 regulate maize mesocotyl elongation and higher altitude adaptation." This study marks the first cloning of a quantitative trait locus (QTL) responsible for regulating maize mesocotyl elongation, confirming the regulatory role of the maize CCT-like transcription factor family gene ZmCCT2 in maize mesocotyl elongation. The study delves into the molecular and genetic mechanisms by which ZmCCT2 and its natural variantion ZmCCT2TypeA positively regulate maize mesocotyl elongation and adaptation to higher altitude.