30-Jul-2025
T cell senescence in the tumor microenvironment
FAR Publishing LimitedPeer-Reviewed Publication
This review synthesizes current knowledge on the triggers and characteristics of T cell senescence in the tumor microenvironment (TME), elucidates how senescent T cells interact with other immune cells, and assesses the impact of these cells on tumor prognosis. In addition, this review systematically examines targeted therapeutic strategies aimed at mitigating the detrimental effects of T cell senescence on cancer treatment.
- Journal
- Cancer Immunology Research
- Funder
- Natural Science Foundation of Guangdong Province, National Natural Science Foundation of China, Guangdong Basic and Applied Basic Research Foundation, Science and Technology Program of Guangzhou, Hunan Youth Science and Technology Talent Project