In a new research paper published in MedComm-Oncology, the team of Yongsheng Li/Dairong Li/Huakan Zhao provided an effective and accurate ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) tool for the simultaneous detection of aumolertinib, osimertinib, gefitinib and their major metabolites, demonstrating the great bioavailability and tissue distribution characteristics of aumolertinib.

In a ground-breaking new development, researchers have created conductive films by mixing conductive polymers with two-dimensional carbon materials. These films can be used as electrodes to monitor a wide range of body signals when pasted on the surface of human skin, including cardiac, myoelectric, and ocular signals.

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have recently developed a novel lysosomal strategy for clearing viruses and their variants. This lysosomal “TRAP” (lysoTRAP) shows potential for inhibiting infection by viruses and variants in cell, mouse, hamster, and human lung organoid models.

Researchers identify potential genes linking depression to menstrual pain

China focuses on improving air quality via the coordinated control of fine particles and ozone

 Researchers have developed the CATCH-LIFE-MELD (Chinese Acute-on-Chronic Liver Failure Consortium-Model for end-stage liver disease) score, an improved prognostic tool for acute-on-chronic liver failure (ACLF). By incorporating age, neutrophil count, and hepatic encephalopathy grade into the traditional MELD score, this model offers more accurate predictions of 28- and 90-day mortality, outperforming current methods. This advancement aids in identifying high-risk patients, optimizing treatment strategies, and guiding future therapies, promising better outcomes for those with ACLF.

Scientific research offers solutions to combat disease with novel treatment options. It is vital to the well-being of humanity, as advancements in medical technology have far-reaching impacts on global health. The Hong Kong Polytechnic University (PolyU) has received support from the French National Research Agency (Agence Nationale de la Recherche)/Research Grants Council Joint Research Scheme (ANR/RGC JRS) - 2024/25 Exercise to conduct an innovative project focused on Osteoarthritis treatment.

In a significant advancement for industrial technology, scientists have introduced a revolutionary digital twin (DT) platform designed to transform the process industry.

In a paper published in National Science Review, Professor Yong Cui and colleagues reported the utility of covalent organic frameworks (COFs) in manipulating electron spin for spin-dependent catalysis via chiral-induced spin selectivity (CISS). Oxygen evolution can be facilitated by tailoring electroactivity of COFs. These chiral COFs can serve as efficient spin filters, reducing the overpotential of oxygen evolution and improving the Tafel slope. This enhanced spin-dependent OER activity stems from its excellent redox-activity, good electron conductivity and effective suppression effect on the formation of H₂O₂ byproducts.

A recent paper in National Science Review by an international team of scientists explores how future warming in different ocean basins may impact the Hadley circulation—a crucial component of the global climate system. The study identifies warming in the tropical Indian Ocean as the primary driver of future changes in this circulation, while variations in tropical Pacific warming add to uncertainties in climate projections.