When AI learns to 'simulate' the brain: a paradigm shift in neuroscience research
Peer-Reviewed Publication
Updates every hour. Last Updated: 9-Dec-2025 00:11 ET (9-Dec-2025 05:11 GMT/UTC)
Artificial intelligence is reshaping brain modeling. This review introduces a unified framework where AI functions as a surrogate brain by integrating dynamical modeling, inverse problem solving, and model evaluation. Trained on neural data, surrogate brains can accurately predict large-scale brain activity and support system analysis, virtual experiments, and model-guided neurostimulation.
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