Yeast cell factory developed to convert methanol into L-lactate
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Updates every hour. Last Updated: 9-Dec-2025 00:11 ET (9-Dec-2025 05:11 GMT/UTC)
Recently, addressing the inherent timescale mismatch challenge between fast and slow responses in optoelectronic sensors, a collaborative team from Suzhou Institute of Nano-Tech and Nano-Bionics (SINANO), Chinese Academy of Sciences (Yukun ZHAO, Shulong LU, Min JIANG), Fudan University (Lifeng BIAN), and Suzhou University of Science and Technology (Jianya ZHANG) has proposed an innovative monolithic integration scheme. By combining surface defect introduction and local contact interface design with a gallium nitride (GaN) nanowire lift-off technique that eliminates the interference from the underlying silicon substrate, the team integrates fast and slow responses into a single device. This results in a transparent bifunctional device capable of self-driven detection and neural synaptic integration, with omnidirectional (360°) detection capability. As a photodetector, the device demonstrates the millisecond-level response speeds, while it exhibits the second- to minute-level relaxation time as an artificial synapse, achieving an over 1000-fold contrast in response dynamics. The device has been validated in the intelligent perception systems for humanoid robots successfully, advancing the development of multifunctional monolithic optoelectronic devices and providing a solid foundation for further research in related fields.
The work entitled "A dual-mode transparent device for 360° quasi-omnidirectional self-driven photodetection and efficient ultralow-power neuromorphic computing" was published in Light: Science & Applications.
A global collaboration including Sunwoda, Chery, Nobel laureate M. Stanley Whittingham, Semitronix, the University of Delaware, and Advance Power, has proposed the "Integrated Battery Large Model," the first AI-driven paradigm covering the entire lithium-ion battery lifecycle. Published in National Science Open, the work outlines a new paradigm for intelligent battery design, manufacturing optimization, defect diagnosis, and lifecycle management through multi-modal AI and simulation synergy.
High-resolution full-color quantum dot light-emitting diode (QLED) displays still face significant challenges, particularly limitations in restricted pixelation manufacturing process and the operational longevity of specific pixels. Researchers have developed a single-layer color-tunable QLEDs technology that achieves color-tunable emission via operating voltage adjustment, avoiding complex tandem structures while demonstrating record-breaking external quantum efficiency (EQE) and broad color gamut including standard white emission, highlighting significant potential for application in full-color display and lighting technologies.
Regurgitation in insects is generally regarded as having digestive and defensive functions. Despite a significant aversion of locust regurgitation to some predators, the defensive mechanisms against predators remain unclear. Now, writing in the journal SCIENCE CHINA Life Sciences, a team of researchers from Hebei University reveals the basis of this defense. According to the study, a specific mixture of three compounds in locust regurgitation deters predators like fire ants by stimulating their gustatory responses. The findings could provide insights into prey-predator interactions and insect defense strategies.
Postnatal growth retardation (PGR) has a high incidence during early postnatal development of piglets and humans, inducing long-term impacts on development and a higher risk for adulthood metabolic syndromes. However, the mechanism of PGR remains unclear. Gut microbiota is crucial in early-life development in humans and animals, but microbiome-induced host growth retardation remains incomplete. Here, researchers from Hunan Agricultural University found that hindgut-enriched Methanobrevibacter smithii compromises the weight gain in the pig PGR model. This finding provides new insight into the contributions of abnormal microbiota to growth retardation.
Fatty liver disease, hepatitis, hepatocellular carcinoma (HCC), and other major liver diseases are significant global public health challenges. Understanding what drives these diseases and exploring targeted therapies is of critical importance. Recently, in the journal Science China Life Sciences, a team from Shandong Second Medical University in collaboration with Shanghai Jiao Tong University published an online review titled "Deubiquitinases in liver diseases: from mechanisms to targeted therapy". This review systematically elucidates the central roles and therapeutic advances related to deubiquitinases (DUBs) in various liver diseases.
Researchers developed a new, symmetry-consistent way to describe CP-violating neutral triple gauge couplings, correcting problems in the conventional approach since 1999. Using systematic simulations of the e⁺e⁻ → Zγ process, they demonstrated that CP-violating effects have distinctive angular distributions in the Z-boson decay. With optimized observables and polarized beams, the proposed colliders can probe new physics at the multi-TeV scale, offering a powerful indirect window beyond the Standard Model.