Expanding the genetic toolkit: nitrogen-response promoters developed for Bacillus licheniformis
Peer-Reviewed Publication
Updates every hour. Last Updated: 3-Nov-2025 02:11 ET (3-Nov-2025 07:11 GMT/UTC)
Using genomic analysis, researchers discovered novel nitrogen-responsive promoters in Bacillus licheniformis, achieving the high-level secretory expression of glutamine transaminase in B. licheniformis for the first time.
Tilted metasurface nanostructures, with excellent physical properties and enormous application potential, pose an urgent need for manufacturing methods. Here, electric-field-driven generative-nanoimprinting technique is proposed. The electric field applied between the template and the substrate drives the contact, tilting, filling, and holding processes. By accurately controlling the introduced included angle between the flexible template and the substrate, tilted nanostructures with a controllable angle are imprinted onto the substrate, although they are vertical on the template. By flexibly adjusting the electric field intensity and the included angle, large-area uniform-tilted, gradient-tilted, and high-angle-tilted nanostructures are fabricated. In contrast to traditional replication, the morphology of the nanoimprinting structure is extended to customized control. This work provides a cost-effective, efficient, and versatile technology for the fabrication of various large-area tilted metasurface structures. As an illustration, a tilted nanograting with a high coupling efficiency is fabricated and integrated into augmented reality displays, demonstrating superior imaging quality.
Recent years have witnessed transformative changes brought about by artificial intelligence (AI) techniques with billions of parameters for the realization of high accuracy, proposing high demand for the advanced and AI chip to solve these AI tasks efficiently and powerfully. Rapid progress has been made in the field of advanced chips recently, such as the development of photonic computing, the advancement of the quantum processors, the boost of the biomimetic chips, and so on. Designs tactics of the advanced chips can be conducted with elaborated consideration of materials, algorithms, models, architectures, and so on. Though a few reviews present the development of the chips from their unique aspects, reviews in the view of the latest design for advanced and AI chips are few. Here, the newest development is systematically reviewed in the field of advanced chips. First, background and mechanisms are summarized, and subsequently most important considerations for co-design of the software and hardware are illustrated. Next, strategies are summed up to obtain advanced and AI chips with high excellent performance by taking the important information processing steps into consideration, after which the design thought for the advanced chips in the future is proposed. Finally, some perspectives are put forward.
Recently, the iGaN Laboratory led by Professor Haiding Sun at the School of Microelectronics, University of Science and Technology of China (USTC) of Chinese Academy of Sciences(CAS), together with a global collaborative team from Wuhan University, Zhejiang University and University of Cambridge, has successfully developed the first miniaturized ultraviolet (UV) spectrometer and realized on-chip spectral imaging. Based on a novel gallium nitride (GaN) cascaded photodiode architecture and integrated with deep neural network (DNN) algorithms, the device achieves high-precision spectral detection and high-resolution multispectral imaging. With a response speed on the nanosecond scale, it sets a new world record for the fastest reported miniaturized spectrometer. The work was published online in Nature Photonics on September 26, 2025.
In a comprehensive review that spans two decades, researchers are examining the profound impact of technological innovation on the journey towards carbon neutrality. The study, titled "Impact of Technological Innovation on Carbon Neutrality: Systematic and Bibliometric Review of Two Decades of Research," is led by Prof. Ephraim Bonah Agyekum from the Department of Nuclear and Renewable Energy at Ural Federal University Named After the First President of Russia Boris Yeltsin in Ekaterinburg, Russia. This review, conducted in collaboration with the Applied Science Research Center at Applied Science Private University in Amman, Jordan, and Tashkent State University of Economics in Tashkent City, Uzbekistan, offers a detailed analysis of how technological advancements have shaped the path to carbon neutrality.
As affordable alternatives to lithium-ion batteries, potassium-ion batteries (PIBs) face problems such as safety issues, limited lifespan, and electrolyte incompatibility with high-capacity electrodes. A non-flammable electrolyte using fluorinated triethyl phosphate (FTEP) as a weakly solvating solvent to create an anion-rich solvation sheath around potassium ions was developed. This innovation facilitates stable potassium plating, efficient K+ insertion into graphite, and prevents aluminum corrosion, paving the way for safer and more durable PIBs.
A computational framework integrates electrochemical lithium-ion intercalation dynamics with mechanical stress evolution in battery materials, addressing a critical gap in solid-state battery design. The specific aspect of coating material for silicon particles in anode layer is investigated, and the key parameters, including coating thickness and strength are systematically analyzed.