Based on a symmetry-guided synthesis strategy, the research group of Professor Yefeng Tang at Tsinghua University recently achieved the efficient construction of the tricyclic core skeleton of polycyclic aromatic tetralin-type lignans by using as key steps the chiral phosphoric acid-catalyzed photoasymmetric [2+2] cycloaddition and ring strain-driven oxidative ring expansion reactions. They also achieved the efficient enantioselective total synthesis of multiple aromatic tetralin-type lignan natural products through subsequent biomimetic cyclization and local desymmetrization reactions. These results were published as an open access article in CCS Chemistry, the flagship journal of the Chinese Chemical Society.

In a pioneering effort to enhance our understanding of carbon storage in wetland ecosystems, researchers are utilizing advanced satellite technology to estimate carbon stocks in the reed wetlands of Weishan County, China. The study, titled "Estimation of Carbon Stock in the Reed Wetland of Weishan County in China Based on Sentinel Satellite Series," is led by Prof. Jie Chen from the College of Oceanography and Ecological Science at Shanghai Ocean University in Shanghai, China, and the State Key Laboratory of Resources and Environmental Information System at the Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences (CAS) in Beijing, China. This research offers valuable insights into the carbon sequestration potential of these vital ecosystems.

Soil pollution from pesticides, pharmaceuticals, and industrial chemicals is a growing threat to global food security and public health. With nearly 80 percent of agricultural soils containing traces of organic contaminants, researchers are looking for sustainable ways to restore damaged land. A new study in Biochar highlights an emerging solution that pairs plant-microbe partnerships with biochar, an engineered carbon-rich material—to detoxify polluted soils while supporting plant growth and economic resilience.

Engineers and scientists, as well as artists, have long been inspired by the beauty and functionality of nature’s designs. Japan designed high-speed trains to cut through the air as smoothly as the kingfisher cuts through water, for example, but useful designs can also be found at a microscopic level. The study of biology in combination with materials science is called biomateriomics. An Italian research team sees great potential in the application of generative artificial intelligence to this already interdisciplinary field. They have described this potential, and the associated limitations and challenges, in an open access review article titled “Generative Artificial Intelligence for Advancing Discovery and Design in Biomateriomics,” published May 1 in Intelligent Computing, a Science Partner Journal.

Tetrandrine, a compound isolated from the root of a traditional Chinese medicine (TCM) Stephania tetrandra, has shown promise in combating Ebola virus infection in previous studies. Its precise mechanism of action, however, had remained unclear. Researchers from The Hong Kong Polytechnic University (PolyU) have discovered that tetrandrine works by blocking the transport of sphingosine – a lipid molecule essential for cellular signalling – and inhibiting the calcium channels. Their research has revealed the critical mechanism of tetrandrine for the first time, opening new avenues for drug discovery and disease treatment.

CHIKVdb is a comprehensive genomic database developed to address limitations in existing resources for chikungunya virus (CHIKV) surveillance and outbreak response. It integrates 8,193 nucleotide and 10,637 protein sequences from 99 countries over 40 years, accompanied by standardized metadata. The platform features an interactive web interface with tools for phylogenetic analysis, source tracing, SNP identification, and genotype identification, streamlining workflows for public health and research applications. Global analyses reveal spatiotemporal heterogeneity in CHIKV transmission, highlighting the predominance of ECSA and ECSA-IOL genotypes and the central role of human and mosquito hosts. CHIKVdb enhances genomic surveillance by providing curated data and analytical capabilities, supporting efforts in pandemic preparedness and targeted control strategies. The database is freely accessible at https://nmdc.cn/gcpathogen/chikv.

A review paper by scientists at the University of Oxford highlights recent advancements in SMTE, including innovations in scaffold design, cell sourcing, usage of external physicochemical cues, and bioreactor technologies.

The review paper, published on May. 15, 2025 in the journal Cyborg and Bionic Systems, presented the emerging synergies between SMTE and robotics, focusing on the use of robotic systems to enhance bioreactor performance and the development of biohybrid devices integrating engineered muscle tissue.

A research paper by scientists at Duke University proposed a novel sharp-edge acoustofluidic platform designed for rapid and effective sample preparation, coupled with sensitive detection of specific sEV populations based on their surface markers.

The new research paper, published on July. 17 in the journal Cyborg and Bionic Systems, presented an acoustofluidic technology which enables highly flexible, specific, and efficient capture and detection of circulating extracellular vesicles (sEVs) from small sample volumes. Its portability, low cost, and ease of use make it an ideal tool for point-of-care detection of sEV surface markers, while its modular design allows for one-step, high-throughput capture and detection of diverse sEV populations

An international team of researchers has reviewed the latest advances in multimodal artificial intelligence (AI) for cardiovascular diseases (CVD), highlighting its superior diagnostic accuracy, risk prediction, and therapeutic guidance compared with traditional single-data approaches. The review outlines how integrating imaging, genomics, electronic health records, and wearable data into unified AI models can enable earlier diagnosis, personalized therapy, and continuous remote monitoring, heralding a new era of precision cardiology.