Common food preservative linked to kidney injury through disrupted cellular crosstalk
Peer-Reviewed Publication
Updates every hour. Last Updated: 25-Dec-2025 06:11 ET (25-Dec-2025 11:11 GMT/UTC)
A new study published in iMetaMed reveals that potassium sorbate, a common food preservative, may cause acute kidney injury by disrupting intercellular communication. Using an integrated approach combining network toxicology, machine learning, and single-cell RNA sequencing, researchers identified the amyloid precursor protein as a central mediator of kidney damage, interacting with immune cells via specific signaling axes.
A new Chinese expert consensus provides critical guidance for using medical imaging to determine whether pancreatic ductal adenocarcinoma (PDAC) can be surgically removed. The consensus, developed by the Group of Abdomen of the Chinese Society of Radiology, emphasizes a multidisciplinary team (MDT) approach and outlines specific imaging techniques for accurate staging. Key recommendations establish contrast-enhanced CT as the primary tool for assessing local tumor spread, while MRI is prioritized for detecting elusive liver metastases. The guidelines also address the limitations of current imaging in evaluating treatment response and highlight the role of diagnostic laparoscopy. This standardized framework aims to improve preoperative planning, personalize treatment strategies, and ultimately enhance patient outcomes across China.
Deciphering true active sites under identical mass transport conditions is crucial for understanding catalytic mechanisms. By establishing uniform mass transfer and implementing controlled experiments to eliminate interfering factors, the research team identified Cu(100) grain boundaries as the key sites driving efficient C2+ production. Advanced characterization and theoretical calculations confirmed these sites facilitate asymmetric C–C coupling between *CHO and *CO intermediates, providing critical insights for rational catalyst design.
To achieve compact yet high-quality imaging, scientists in Tongji University and Stanford University, have developed a neural array meta-imaging system that overcomes long-standing optical trade-offs. The 2.76-mm single-metalens camera captures real-time full-color video at 25 Hz with image quality comparable to commercial lenses. This breakthrough paves the way for ultrathin, high-performance, and intelligent imaging systems, advancing next-generation optical technologies for mobile, industrial, and aerospace applications.
Chinese chemists boost lignin’s sun protection factor from 5 to 66 and cut colour darkness by one-third through controlled radical grafting and TiO₂ nano-loading, offering a biodegradable alternative to petrochemical filters.
Reporting in the Journal of Bioresources and Bioproducts, researchers show that atom-transfer radical polymerisation couples waste-pulp lignin with the commercial UV absorber MBBT, producing sub-micron spheres that remain stable after three hours of intense ultraviolet irradiation.
A Canadian team turned 23,000 mating types into a materials library, showing nuclear-mitochondrial combos double film strength or ductility depending on cross-linker choice.
Writing in the Journal of Bioresources and Bioproducts, researchers report the first systematic screen of wild fungal genotypes for pure mycelial materials, proving that strain choice can outperform process tweaks in green fabrication.
Italian scientists melt-blend lignin scorched in a gliding-arc tornado into polypropylene, doubling toughness and keeping 98 % of strength after two re-extrusions without any chemical compatibilizer.
Reporting in the Journal of Bioresources and Bioproducts, researchers show that a 30-second argon-plasma whirl cuts hydroxyl groups on lignin by one third, spawns phenoxy radicals and forges stronger bonds with polypropylene, yielding recyclable, high-performance green composites.