Global mortality and disability burden from 1990 to 2021: contrasting patterns across development levels and the roles of population growth and ageing
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Oct-2026 22:15 ET (23-Oct-2026 02:15 GMT/UTC)
GBD 2021 data were used to assess trends, SDI-related distributions and DALY drivers from 1990 to 2021. Cardiovascular diseases had the highest mortality and DALY rates in 2021. Communicable, maternal, neonatal and nutritional (CMNN) burdens remained concentrated towards lower-SDI settings but gradients weakened, whereas NCD burdens remained concentrated towards higher-SDI settings and gradients strengthened. Population growth and ageing mainly drove the 577 million rise in NCD-related DALYs.
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