Key targets and pathways in skin photoaging: a comprehensive review
Peer-Reviewed Publication
Updates every hour. Last Updated: 24-Dec-2025 20:11 ET (25-Dec-2025 01:11 GMT/UTC)
This review explores skin damage from UV, visible light, and infrared radiation, details key photoaging mechanisms (oxidative stress, SASP, DNA damage, etc.), and puts forward three novel photoprotection strategies, providing a theoretical basis for developing effective sun protection products.
Researchers from China have developed a solar-driven multi-field synergistic strategy to simultaneously harvest freshwater and boron from seawater. The innovative (MXene-MgO)@sodium alginate (SA) composite gel (MMS) achieves high evaporation rates and boron adsorption capacities, offering a sustainable solution to global water and food scarcity.
Metal hydrides with high hydrogen density provide promising hydrogen storage paths for hydrogen transportation. However, the requirement of highly pure H2 for re-hydrogenation limits its wide application. Here, amorphous Al2O3 shells (10 nm) were deposited on the surface of highly active hydrogen storage material particles (MgH2–ZrTi) by atomic layer deposition to obtain MgH2–ZrTi@Al2O3, which have been demonstrated to be air stable with selective adsorption of H2 under a hydrogen atmosphere with different impurities (CH4, O2, N2, and CO2). About 4.79 wt% H2 was adsorbed by MgH2–ZrTi@10nmAl2O3 at 75 °C under 10%CH4 + 90%H2 atmosphere within 3 h with no kinetic or density decay after 5 cycles (~ 100% capacity retention). Furthermore, about 4 wt% of H2 was absorbed by MgH2–ZrTi@10nmAl2O3 under 0.1%O2 + 0.4%N2 + 99.5%H2 and 0.1%CO2 + 0.4%N2 + 99.5%H2 atmospheres at 100 °C within 0.5 h, respectively, demonstrating the selective hydrogen absorption of MgH2–ZrTi@10nmAl2O3 in both oxygen-containing and carbon dioxide-containing atmospheres hydrogen atmosphere. The absorption and desorption curves of MgH2–ZrTi@10nmAl2O3 with and without absorption in pure hydrogen and then in 21%O2 + 79%N2 for 1 h were found to overlap, further confirming the successful shielding effect of Al2O3 shells against O2 and N2. The MgH2–ZrTi@10nmAl2O3 has been demonstrated to be air stable and have excellent selective hydrogen absorption performance under the atmosphere with CH4, O2, N2, and CO2.
High‐entropy amorphous catalysts (HEACs) integrate multielement synergy with structural disorder, making them promising candidates for water splitting. Their distinctive features—including flexible coordination environments, tunable electronic structures, abundant unsaturated active sites, and dynamic structural reassembly—collectively enhance electrochemical activity and durability under operating conditions. This review summarizes recent advances in HEACs for hydrogen evolution, oxygen evolution, and overall water splitting, highlighting their disorder-driven advantages over crystalline counterparts. Catalytic performance benchmarks are presented, and mechanistic insights are discussed, focusing on how multimetallic synergy, amorphization effect, and in‐situ reconstruction cooperatively regulate reaction pathways. These insights provide guidance for the rational design of next‐generation amorphous high‐entropy electrocatalysts with improved efficiency and durability.
Endometriosis is a chronic gynecological disease requiring relatively long therapy of at least 3 to 6 months, and has a high recurrence rate. Further research using animal models is needed to better understand the disease. During the COVID-19 pandemic, laparoscopic surgeries were suspended to minimize infection risk. This study aims to establish an experimental animal model of endometriosis using stored chocolate cyst pulp. This laboratory experimental study included 12 female Mus musculus mice. Immunodeficient mice were intraperitoneally injected with a previously prepared chocolate cyst slurry. On the 15th day, the mice were euthanized, and anatomical pathological examination was performed using hematoxylin and eosin (HE) staining.