A groundbreaking study introduces a novel Transformer-based time-series framework designed to predict daily risk alerts for sepsis patients in the Intensive Care Unit (ICU). This model, leveraging sequential data from the eICU database, dynamically captures evolving health trajectories, enabling real-time identification of high-risk patients and actionable insights for personalized interventions. The study, titled “Predictive model for daily risk alerts in sepsis patients in the ICU: visualization and clinical analysis of risk indicators” published in Precision Clinical Medicine February 8, 2025, demonstrates exceptional predictive power, with an AUC increasing from 0.87 on admission day to 0.92 by day 5, offering a new paradigm for ICU prognostics.

This study shows that the SAAR diet regulates glucose and lipid metabolism to support weight control without impacting appetite or physical activity (Figure 1), offering new insights into obesity management. The potential benefits and risks of a low-SAA diet in humans require further research to validate its molecular mechanisms and assess its clinical applications.

This research not only brings new hope for sustainable agricultural production but also lays a strong scientific foundation for future ecosystem service management. The complexity of soil micro-food webs and their impact on soil fertility is undoubtedly a crucial topic for future agricultural research and practice. Media and the public should pay attention to these findings, as they have the potential to revolutionize agricultural practices and address the dual challenges of food security and environmental protection.

A new study reveals that Epstein-Barr virus (EBV) infection exacerbates ulcerative colitis (UC) by driving macrophage pyroptosis through the upregulation of glycolysis. This finding provides a potential therapeutic target for mitigating EBV-induced intestinal inflammation. The study, titled "Epstein-Barr virus infection exacerbates ulcerative colitis by driving macrophage pyroptosis via the upregulation of glycolysis," was published on January 21, 2025, in Precision Clinical Medicine.

A team of researchers from Huazhong University of Science and Technology has systematically reviewed the key scientific technologies of construction robots in extreme environments, summarized the research advancements, and discussed future research directions. The research article detailing these innovations, titled "Construction Robotics in Extreme Environments: From Earth to Space," has been published in the prestigious journal Engineering.

A recent review in Engineering presents new methods for enhancing chiral optical signals. Chirality is important in many fields, but its optical signals are weak and hard to measure. The research covers strategies like tailoring optical fields, using photonic resonance, orbital angular momentum (OAM) beams, metasurfaces with bound states in the continuum (BICs), and nonlinear optics. These methods offer new ways to study chiral optics, though challenges remain.

A team from China Agricultural University has developed a novel synergetic cooling and charging strategy for high-power direct current fast charging in electric vehicles. Published in Engineering, the approach uses a gallium-based liquid metal flexible charging connector (LMFCC). This new solution aims to overcome the challenges of thermal shocks and inefficient cooling during high-current charging, with promising results in improving charging system performance.

A review in Engineering explores organ preservation, which is a critical area due to the global organ shortage. Current methods like static cold storage and machine perfusion have limitations. Cryopreservation shows promise, but challenges remain. The research details the history, techniques, and prospects for different organs, aiming to improve preservation and address the shortage.

The effect of high magnetic field on the directional solidification structure of Al-18 at.%Ni peritectic alloy was studied. In the absence of magnetic field, the alloy forms a dendritic structure with preferred orientation, and a transverse plate-like structure with block eutectic is formed under a 6 T magnetic field. At 0 T and 5 μm/s, the Al₃Ni phase was preferentially oriented along the <010> direction, while the sample prepared at 100 μm/s exhibited no preferred orientation. Under 6 T magnetic field, 5 μm/s pulling makes the solidification mode change from peritectic reaction to hypereutectic reaction, and the Al₃Ni phase presents orientation. When the pumping speed increases to 20-100 μm/s, the peritectic reaction is still dominant. The primary Al₃Ni₂ phase is oriented along the direction, and the peritectic phase is attached to it to form a preferred orientation. The magnetic field regulates crystal orientation and solute transport through the coupling of magnetic torque, thermo-electro-magnetic force and magnetic field force, and its influence mechanism shows a significant dependence on pulling speed.

This study, published in Earth and Planetary Physics, explores the subduction thermal state, slab metamorphism, and seismic activity in the Makran Subduction Zone. Using 3-D thermal modeling, the research examines the thermal structure of the subducting slab, the resulting metamorphic processes, and their relationship to earthquake generation. The findings provide crucial insights into the dynamics of subduction zones, with significant implications for understanding seismic hazards in the region.